Prospective Analysis of Introperative RegenLab PRP and Hyaluronic Acid in Patients With Knee ACL Tear
试验速览
- 阶段
- 4 期
- 入组人数
- 150
- 试验地点
- 2
- 主要终点
- 150 of participants with preoperative and postoperative Magnetic Resonance Imaging are accessed
研究概览
简要总结
Purpose: The purpose of this article is to examine the clinical application of PRP and PRP+hyaluronic acid in disorders in the knee.
Methods:
The study was conducted on 150 adult patients with age over 20 years old affected by unilateral ACL complete tear and receiving ACL reconstruction. We divided the patients in three groups, and we treated the group A with perioperative injection of HHA, group B with perioperative HHA+PRP, group C with perioperative normal saline.
Follow-up:
Every 1,3,and 12months, we recheck physical exmianation at OPD and recheck MRI at postoperative 3 months.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •receiving unilateral ACL reconstruction in our hospital
- •postoperative follow-up over 3 month
排除标准
- •postoperative follow-up less than 3 month
- •possible pregnency
- •with coagulation disease
- •NSAIDs intake during study period
结局指标
主要结局
150 of participants with preoperative and postoperative Magnetic Resonance Imaging are accessed
时间窗: postoperative 3 month
anterior cruciate ligament was accessed by MRI T1 and T2 image; MRI was checked by one orthopedist
150 of participants with preoperative and postoperative physical examination are accessed by anterior drawer test and Lachman test
时间窗: postoperative 12 months
the investigators recheck physical exmianation of participants at OPD; physical examination was checked by one orthopedist
次要结局
未报告次要终点
研究者
Yi Ping Wei
Chief resident, Orthopedics department, Kaohsiung Veterans General Hospital; Principal Investigator
Kaohsiung Veterans General Hospital.