Effects of Neurorehabilitation on Upper Limb Performance and on Fatigue in People With Multiple Sclerosis
试验速览
- 阶段
- 不适用
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- Change from Baseline in Heart Rate at 2 and 4 months
研究概览
简要总结
In Multiple Sclerosis the multiplicity of physical and psychological dysfunctions have been shown to exhibit a number of life-altering problems such as fatigue, limb weakness, alteration of upper extremity fine motor coordination, loss of sensation, spasticity. These problems affect performance of many daily living activities (ADL) such as dressing, bathing, self-care, and writing, thus reducing functional independence and self-rated quality of life.
Twenty people with Multiple Sclerosis will receive neurorehabilitation treatment comprising a combination of aerobic training and upper limb task-oriented training.
The aim of this pilot crossover study is to evaluate the effects of neurorehabilitation on upper limb performance and on fatigue in People with Multiple Sclerosis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosis of Multiple Sclerosis
- •no relapses in the last three months
- •Expanded Disability Status Scale (EDSS) ≤ 8;
排除标准
- •subjects with relapses
- •worsening of the pathology in the last three months
- •subjects with cognitive and psychiatric disturbances
- •subjects with cardiovascular disease
结局指标
主要结局
Change from Baseline in Heart Rate at 2 and 4 months
时间窗: baseline, then participants were followed for the duration the outpatient treatment protocol, an average of 8 weeks, and at follow up 2 months after the end of the treatment protocol
Change from Baseline in 9-hole peg test at 2 and 4 months
时间窗: baseline, then participants were followed for the duration the outpatient treatment protocol, an average of 8 weeks, and at follow up 2 months after the end of the treatment protocol
次要结局
未报告次要终点