Application of Early Bundle Management of Mechanical Ventilation to Prevent Ventilator Dependence in Children
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- limb skeletal muscle function indexes
研究概览
简要总结
This study is based on the risk factors of previous studies to formulate a bundle treatment plan to prevent ventilator dependence in children, in order to reduce the proportion of ventilator dependence in children and provide a theoretical basis for reasonable intervention of children with mechanical ventilation.
Participants will receive intensive rehabilitation, nutrition, and tracheotomy at different time periods.
Researchers will compare the control group to see whether it can reduce the incidence of ventilator dependence
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 28 Days 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •（1）All stable children receiving mechanical ventilation
- •（1）Stable condition: respiratory rate does not exceed 20% of the basic respiratory rate, PEEP<
- •60%, VIS score< 20, there is no hypotension (70mmHg+ age ×2, 70mmHg under one year old), no higher than the P95 of the same sex and age
排除标准
- •Status epilepticus
- •Active intracranial hemorrhage
- •Intracranial hypertension
- •Unstable fracture of the spine
- •Spinal cord injury
- •There are injuries that affect the implementation of rehabilitation
- •Acute surgery was performed on the same day.
- •Body temperature over 40℃
- •Brain function failure
研究组 & 干预措施
intervention group
干预措施: early bedside rehabilitation (Behavioral)
intervention group
干预措施: nutrition program (Dietary Supplement)
intervention group
干预措施: tracheotomy (Procedure)
control group
结局指标
主要结局
limb skeletal muscle function indexes
时间窗: 21 days after enrollment
Skeletal muscle thickness and cross-sectional area were measured
次要结局
未报告次要终点