Povidone Iodine Irrıgation at Hip-Knee Arthroplasty

Not Applicable

Recruiting

• Conditions: Osteoarthritis; Iodine Toxicity; Hyperthyroidism
• Interventions: Procedure: PI solution; Procedure: Saline Solution

• Registration Number: NCT05599841
• Lead Sponsor: Ankara University

Brief Summary

Povidone iodine (PI) solution is an antimicrobial solution that can be used at hip and knee arthroplasty cases. It contains iodine that may be absorbed by the body. This study aims to investigate any absorption caused by PI solution.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-01-01
• Study First Submitted: 2022-10-26
• Study First Submitted QC: 2022-10-26
• Study First Posted: 2022-10-31
• Primary Completion: 2023-05-31
• Status Verified: 2023-09
• Study Completion: 2023-09-16
• Last Update Submitted: 2023-09-16
• Last Update Posted: 2023-09-21

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

• All patients with hip/knee osteoarthritis who undergo primary arthroplasty

Exclusion Criteria

• Patients with abnormal thyroid function tests in the preoperative period, a history of the previous thyroid-related disease.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Povidone Iodine Solution	PI solution	The group whom PI solution will be used at surgery
Saline Solution	Saline Solution	The group whom only saline solution will be used at surgery

Primary Outcome Measures

Name	Time	Method
Urine iodine level	postoperative first day	Urine iodine concentration

Secondary Outcome Measures

Name	Time	Method
Thyroid hormone	postoperative 14 days	Blood thyroid hormone levels including: TSH, T3 and T4

Trial Locations

Locations (1)

Ankara University Faculty of Medicine; 🇹🇷 Ankara, Turkey