Effect of Neurodynamics Nerve Flossing on Femoral Neuropathy in Haemophilic Patients

Not Applicable

Completed

• Conditions: Femoral Neuropathy in Haemophilic Patients
• Interventions: Other: Neurodynamics Nerve flossing; Other: conventional selected exercise program

• Registration Number: NCT04448275
• Lead Sponsor: Lama Saad El-Din Mahmoud

Brief Summary

To investigate the effect of Neurodynamics Nerve flossing on femoral neuropathy in patients with haemophilia

Background: heamophilia is one of the serious chronic disorders in children and adolescents which results in less physical activities and restlessness hours than their peer.

HYPOTHESES:

This study will hypnotize that:

Neurodynamics Nerve flossing will have a significant effect on femoral neuropathy in patients with haemophilia

RESEARCH QUESTION:

will the Neurodynamics Nerve flossing has an effect on femoral neuropathy in patients with haemophilia?

Detailed Description

Haemophilic patients with Femoral Neuropathy will be randomly divided in two equal groups control group which will receive conventional selected exercise program and study group will receive the same exercise training program in addition to Neurodynamics Nerve flossing three times per week for three successive months.

The Evaluation will done pre and post interventions included:

femoral nerve motor conduction velocity, muscle test For Iliopsoas and Quadriceps muscles and Pain visual analogue scale.

Study Timeline

• Study First Submitted: 2020-06-22
• Study First Submitted QC: 2020-06-23
• Study First Posted: 2020-06-25
• Study Start: 2020-06-30
• Primary Completion: 2020-09-30
• Study Completion: 2020-10-30
• Status Verified: 2021-01
• Last Update Submitted: 2021-01-05
• Last Update Posted: 2021-01-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 30

Inclusion Criteria

• hemophilia A or B, all the patients
• positive femoral nerve tension test
• the Manual muscle test for iliopsoas and quadriceps muscles in all patients not less than grade 2 according to the oxford scale
• the age ranging from (12:16) years
• all the participants will be able to communicate verbally ,obey commands and instructions and co-operate with testing and training protocols

Exclusion Criteria

• any participants have auditory, visual and sever cardiac disorders
• Patients who have mild degree of hemophilia
• Patients who have joint, muscle bleeding or pain in the lower limb in the preceding 3 weeks
• patients with any other neurological disorders or musculoskeletal disorders or deformities of the lower limb.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
study group	conventional selected exercise program	received conventional selected exercise program and in addition to Neurodynamics Nerve flossing for femoral nerve
control group	conventional selected exercise program	received conventional selected exercise program in form of: Ultrasound therapy The flexibility exercises for iliopsoas \& quadriceps in heamophilic patient The iliopsoas \& quadriceps muscles strength exercise
study group	Neurodynamics Nerve flossing	received conventional selected exercise program and in addition to Neurodynamics Nerve flossing for femoral nerve

Primary Outcome Measures

Name	Time	Method
Electromyography Nerve conduction study	12 weeks	Femoral Nerve motor conduction velocity (m/sec.) , via the Neuropack S1 MEB9004 EMG device
Femoral Nerve Tension Test, for femoral nerve injury	12 weeks	Femoral Nerve Tension Test is a neural tension test used to stress the femoral nerve; A positive test was be reproduction of the patient's symptoms as burning discomfort in the groin or anterior thigh occurred if there was femoral nerve involvement.
Manual muscle test, Oxford five grades of muscle power assessment	12 weeks	The group Manual muscle test was used for testing the strength of iliopsoas and quadriceps muscles, according to the Oxford Scale as the Muscle strength is often rated on a scale of 0/5 as follow: (0/5) no contraction of muscle, (1/5) muscle flicker contraction, but no movement (2/5) movement possible, but not against gravity (test the joint in its horizontal plane), (3/5) movement possible against gravity, but not against resistance by the therapist, (4/5) movement possible against some resistance by the examiner and (5/5) normal strength

Trial Locations

Locations (1)

October 6 University; 🇪🇬 Giza, El-Sheikh Zayed City Giza 1133 Egypt, Egypt