Gravity assisted continuous flow peritoneal dialysis in children with acute renal failure

Not Applicable

• Conditions: Injury, Occupational Diseases, Poisoning; Paediatrics; Acute kidney injury; Kidney Disease

• Registration Number: PACTR201801003005742
• Lead Sponsor: Peter Nourse

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-01-24
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

Paediatric patients 1 day to 5 years of age in ICU setting

Biochemical criteria of acute kidney injury (AKI): according to the Kidney Injury score (KDIGO) criteria

The decision to start acute dialysis will be made based on the biochemical criteria and the clinical opinion of the pediatric nephrologists and the ICU consultants

Exclusion Criteria

Clinical condition contraindicates procedure of catheter placement PD. E.g. abdominal wall defects, severe diaphragmatic defects, burns or septic skin lesions covering the whole abdominal wall.

Peritonitis only if the catheter is not able to be placed safely.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Clearance of : Urea, creatinine, phosphate, potassium, albumin expressed ml/min/1.73 m2 and KT/V(clearance divided by total body water);Total ultra-filtration rate measured in ml/kg per hour

Secondary Outcome Measures

Name	Time	Method
Mass transport area co-efficient;glucose absorption;Protein loss in grams;dialysate salt removal;Free water transport ;intraperitoneal pressure;cost comparison between intervention and control;complications