Effect of Electric Muscle Stimulation on Patients With Chronic Respiratory Failure
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Chronic Respiratory Failure
- Sponsor
- Mackay Memorial Hospital
- Enrollment
- 13
- Locations
- 1
- Primary Endpoint
- Ventilator-free Days
- Status
- Terminated
- Last Updated
- 6 years ago
Overview
Brief Summary
Background: After mechanical ventilation, 5-20% of patients with acute respiratory failure would depend on ventilator support more than 14 days because of critical-illness weakness and their underlying diseases such as heart failure and chronic obstructive pulmonary disease.
Hypothesis: Electric muscle stimulation(EMS) will improve their muscle strength and shorten their ventilator days.
Design: Randomized controlled trial. Adult patients with mechanical ventilation more than 14 days are eligible. EMS would be applied in experimental group 32 minutes/day on their bilateral thigh.
Detailed Description
Randomized controlled trial involves the adult patients with invasive mechanical ventilation more than 14 days. The participants were not eligible for active rehabilitation because of drowisness or weakness(Medical Research Council (MRC) Scale for Muscle Strength≦ Grade 3). EMS would be applied in experimental group 32 minutes/day on their bilateral thigh(quadriceps muscle).
Investigators
Kuang-Hua Cheng, MD
Visiting staff
Mackay Memorial Hospital
Eligibility Criteria
Inclusion Criteria
- •Adult patient required mechanical ventilation more than 14 days
- •No ability for active endurance exercise because of poor consciousness or limb weakness.
Exclusion Criteria
- •Pregnant women
- •Limb wound/infection interfered with electric pad application
- •Recent acute myocardial infarction or life-threatening arrhythmia
- •Uncontrolled epilepsy
- •Dying patients without attempt of ventilator weaning
- •Absence of respiratory drive
Outcomes
Primary Outcomes
Ventilator-free Days
Time Frame: 28 days
the cumulative ventilator-free days after intervention, in following 28 days.
Secondary Outcomes
- Grip Power(7 days after intervention)