Effect of Electric Muscle Stimulation on Patients With Chronic Respiratory Failure
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 13
- 试验地点
- 1
- 主要终点
- Ventilator-free Days
研究概览
简要总结
Background: After mechanical ventilation, 5-20% of patients with acute respiratory failure would depend on ventilator support more than 14 days because of critical-illness weakness and their underlying diseases such as heart failure and chronic obstructive pulmonary disease.
Hypothesis: Electric muscle stimulation(EMS) will improve their muscle strength and shorten their ventilator days.
Design: Randomized controlled trial. Adult patients with mechanical ventilation more than 14 days are eligible. EMS would be applied in experimental group 32 minutes/day on their bilateral thigh.
详细描述
Randomized controlled trial involves the adult patients with invasive mechanical ventilation more than 14 days. The participants were not eligible for active rehabilitation because of drowisness or weakness(Medical Research Council (MRC) Scale for Muscle Strength≦ Grade 3).
EMS would be applied in experimental group 32 minutes/day on their bilateral thigh(quadriceps muscle).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patient required mechanical ventilation more than 14 days
- •No ability for active endurance exercise because of poor consciousness or limb weakness.
排除标准
- •Pregnant women
- •Limb wound/infection interfered with electric pad application
- •Recent acute myocardial infarction or life-threatening arrhythmia
- •Uncontrolled epilepsy
- •Dying patients without attempt of ventilator weaning
- •Absence of respiratory drive
研究组 & 干预措施
Electric muscle stimulation(EMS)
EMS:use programmed middle frequency electric stimulation device(HELEX 573)for both quadriceps stimulation, 32 minutes per day, 5 time per week.
干预措施: EMS (Device)
Control
Patients with routine passive rehabilitation program.
结局指标
主要结局
Ventilator-free Days
时间窗: 28 days
the cumulative ventilator-free days after intervention, in following 28 days.
次要结局
- Grip Power(7 days after intervention)
研究者
Kuang-Hua Cheng, MD
Visiting staff
Mackay Memorial Hospital