The study is about comparing two drugs Dexmedetomidine and Magnesium sulphate with Levobupivacaine in spinal anesthesia for lower limb surgeries

Not yet recruiting

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2022/05/042400
• Lead Sponsor: Government Medical CollegeBaroda

Brief Summary

This study carry out in Goverment medical college,Baroda.The purpose of study is to compare efficacy of dexmedetomidine and magnesium sulphate as adjuvants to levobupivacaine in spinal anesthesia to see the differences in sensory and motor block characteristics,mainly onset and duration of block along with determining effects on haemodynamics in lower limb orthopedic surgeries.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2022-04-29
• Study Start: 2022-10-05

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1.ASA grade I,II,III 2.Lower limb orthopedic surgeries 3.Duration of surgery 2.5 to 3 hours.

Exclusion Criteria

1.Patient refusal 2.Patient on beta blockers and calcium channel blockers 3.Uncontrolled systemic disease 4.Patient on anti coagulant therapy 5.Pragnant and lactating females 6.Patient with local site infection 7.Patient with allergy to local anesthetics and adjuvants.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
sensory and motor block characteristics	Throught surgery
1.onset of sensory block at L1 dermatomal level(min)	Throught surgery
2.Time to achieve maximum sensory level(mins)	Throught surgery
3.Time for two segment regression(mins)	Throught surgery
4.Total duration of sensory block(time to regress till S1 dermatome	Throught surgery
5.Onset of motor blockade(Bromage 1)(min)	Throught surgery
6.Maximum bromage score(Bromage 3)(mins)	Throught surgery
7.Time to achieve maximum motor blockade(mins)	Throught surgery
8.duratin of motor blockade(mins)	Throught surgery

Secondary Outcome Measures

Name	Time	Method
1.To observe any changes in hemodynamic parameters like pulse rate,blood pressure,respiratory rate,ECG,spo2 perioperatively	2.Duration of effective analgesia-time from administration of drug intrathecally to pain score VAS4 postoperatively

Trial Locations

Locations (1)

Government Medical college,Baroda; 🇮🇳 Vadodara, GUJARAT, India

Government Medical college,Baroda

🇮🇳Vadodara, GUJARAT, India

Dr Vidhi

Principal investigator

9726800401

brahmbhattvidhi15@gmail.com