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A Study on the Characterization of Fatigue Patients after Stroke

Not Applicable
Recruiting
Conditions
Diseases of the nervous system
Registration Number
KCT0003900
Lead Sponsor
Kyung Hee University
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
160
Inclusion Criteria

(1) men or women who are not pregnant or are not breastfed at the age of 19-80 years
(2) Patients diagnosed with cerebral hemorrhage or cerebral infarction via brain computed tomography or magnetic resonance imaging (MRI)
(3) No conscious impairment (Mental Grade I)
(4) Subjects who voluntarily agreed to participate in this trial

Exclusion Criteria

If there are any of the following items, they should be excluded from this study.
(1) Subejcts who diagnosed with degenerative brain disease (eg, Parkinson's disease, Alzheimer's disease)
(2) Patients diagnosed with subarachnoid hemorrhage via brain computed tomography or magnetic resonance imaging (MRI)
(3) Patients who have other brain diseases (eg, brain tumor, traumatic brain injury, arteriovenous malformation, moyamoya disease, stroke due to these diseases, etc.)
(4) Disabled patients who have already suffered from other neurological and muscular disorders
(5) Patients with unstable vital signs during screening (eg, systolic blood pressure of 160 mmHg or more even when taking medications)
(6) Patient with severe illness (eg, cancer, liver disease, kidney disease, severe heart failure (NYHA class III or higher), etc.)
(7) Patients who participated in other clinical trials within 30 days
(8) If the evaluator finds it inappropriate to participate in the screening for other reasons

Study & Design

Study Type
Observational Study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Assessment of autonomic nervous system function (Heart rate variability (HRV), 24-hour ambulatory blood pressure (24ABPM))
Secondary Outcome Measures
NameTimeMethod
Assessment of microcirculation, arteriosclerosis (nailfold capillaroscopy, nail compression test, Cardio-ankle vascular index (CAVI), Ankle-brachial pressure index (ABI), Acceleration pulse wave test);Assessment of depression tendency (Patient Health Questionnaire-9 (PHQ-9), Beck Depression Inventory (BDI));Assessment of cognitive function (Mini-Mental State Examination-Korean (MMSE-K), Clinical Dementai Rating (CDR));Assessement of neurological deficit (Fugl-Meyer Assessment score [Upper limb/Lower limb], National Institute of Health Stroke Scale (NIHSS));Assessement of impact of fatigue (modified Barthel Index (mBI), Modified Fatigue Impact Scale, Stroke Specific Quality of Life (SS-QOL))
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