Correlation of Arterial and Venous Lactate and Base Deficit Values

Completed

• Conditions: Peripheral Access; Central Venous Catheter; Arterial Access
• Interventions: Device: bedside point-of-care device

• Registration Number: NCT02888431
• Lead Sponsor: Joseph D. Tobias

Brief Summary

The purpose of this study is to determine the correlation between pH, base deficit, and lactate values when comparing venous and arterial blood samples in the pediatric population.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-09
• Study First Submitted: 2016-08-17
• Study First Submitted QC: 2016-08-30
• Study First Posted: 2016-09-05
• Primary Completion: 2016-12
• Study Completion: 2016-12
• Status Verified: 2017-01
• Last Update Submitted: 2017-01-30
• Last Update Posted: 2017-01-31

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• Patients requiring arterial access and peripheral access. Additionally, patients with a central venous catheter would be included.

Exclusion Criteria

• Patients who not require arterial access.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
peripheral venous blood sample	bedside point-of-care device	0.5 mL blood sample drawn simultaneously with arterial sample from clinically indicated peripheral line
Arterial blood sample	bedside point-of-care device	0.5 mL blood sample from arterial line which is clinically indicated

Primary Outcome Measures

Name	Time	Method
lactate blood value	During surgery- approximately 15-20 minutes after induction in the operating room (OR)	blood will be drawn from peripheral venous line, arterial line, and/or central venous line then the lactate value will be assessed by using a bedside point-of-care device, called i-stat.
base deficit blood value	During surgery- approximately 15-20 minutes after induction in the operating room (OR)	blood will be drawn from peripheral venous line, arterial line, and/or central venous line then the base deficit blood value will be assessed by using a bedside point-of-care device, called i-stat.
pH blood value	During surgery- approximately 15-20 minutes after induction in the operating room (OR)	blood will be drawn from peripheral venous line, arterial line, and/or central venous line then pH blood value will be assessed by using a bedside point-of-care device, called i-stat.

Trial Locations

Locations (1)

Nationwide Children's Hospital; 🇺🇸 Columbus, Ohio, United States