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A Comparison between Diagnostic Tests for Primary Aldosteronism

Not Applicable
Conditions
Primary Aldosteronism
Registration Number
JPRN-UMIN000037304
Lead Sponsor
Department of Hypertension Research Research Support Center Shizuoka General Hospital
Brief Summary

The plasma aldosterone concentration 60 min after the load of CCT (CCT60-PAC) <=59.0 pg/mL and CCT60-plasma renin activity (PRA) >=1.05 ng/mL/h could predict negativities of SIT and FUP, respectively, with >95% specificities. The present study suggested the SIT as the next test to be done if the CCT-negative patient belonged to the subset with CCT60-PAC >59.0 pg/mL and CCT60-PRA >=1.05 ng/mL/h, otherwise the FUP should be selected.

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
142
Inclusion Criteria

Not provided

Exclusion Criteria

(1) patients for whom less than two of the confirmatory tests were performed, (2) patients who refused to be included in the study upon information disclosure of the study.

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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