Biorepository to Support Research in Kidney Diseases
Overview
- Phase
- Not Applicable
- Status
- Enrolling By Invitation
- Sponsor
- Yale University
- Enrollment
- 1,000
- Locations
- 2
- Primary Endpoint
- Histological diagnosis
Overview
Brief Summary
To support advances in the understanding of pathophysiology and therapies of kidney diseases by creating a BioBank of kidney tissue, DNA, plasma, and urine from patients with kidney diseases.
Detailed Description
A biorepository of human samples to support research to advance understanding of human kidney diseases will be created. Clinically, kidney diseases are detected by blood and urine laboratory tests. However, the underlying cause of kidney disease is often not clear on blood and urine tests. In such cases, a clinician may choose to perform a kidney biopsy to establish the diagnosis. Patients who are scheduled to undergo a kidney biopsy will be invited to participate in this proposed study.
Study Design
- Study Type
- Observational
- Observational Model
- Other
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to 99 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Patients scheduled to undergo a clinically indicated kidney biopsy
- •English or Spanish speaking
Exclusion Criteria
- •Under 18 years or age
- •Known pregnancy
- •Additional vulnerable individuals (incarcerated, institutionalized, or otherwise unable to participate in the study)
- •Inability to provide informed consent
Outcomes
Primary Outcomes
Histological diagnosis
Time Frame: 5 years
Histological diagnosis of kidney disease determined by evaluation by renal pathologists
Secondary Outcomes
- Occurrence of chronic kidney disease, end stage kidney disease or death(10 years)