Study of the Effectiveness of Additional Reductions in Cholesterol and Homocysteine
Not Applicable
Completed
- Conditions
- Coronary heart diseaseCirculatory System
- Registration Number
- ISRCTN74348595
- Lead Sponsor
- niversity of Oxford (UK)
- Brief Summary
2008 Results article in http://www.ncbi.nlm.nih.gov/pubmed/18650507 results 2010 Results article in http://www.ncbi.nlm.nih.gov/pubmed/20571015 results
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 12064
Inclusion Criteria
Men and women who have survivied a heart attack and in whom statin therapy is indicated.
Exclusion Criteria
Age under 18 years or over 80 at invitation, contraindications to either study drug, other predominant medical problem.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Major vascular events (MVEs) during the scheduled treatment period
- Secondary Outcome Measures
Name Time Method MVEs separately during the first year and in the later years of the study, MVEs in patients subdivided by pre-randomisation lipid levels, MVEs in the presence and absence of the other randomised treatments, major coronary events, total strokes