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临床试验/NCT07015606
NCT07015606尚未招募不适用

The Comparative Study of Sciatic Vs Femoral Nerve Mobilization Along With Electrical Muscle Stimulation in Low Back Pain

Shalamar Institute of Health Sciences0 个研究点目标入组 42 人开始时间: 2025年8月28日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
42
主要终点
Visual analog scale (VAS)

研究概览

简要总结

to determine the therapeutic effectiveness of sciatic nerve mobilization compared to femoral nerve mobilization along with electrical stimulation in promoting functional recovery and alleviating symptoms in patients with low back pain and to reveal which one is more effective for pain relief and functional improvement in low back pain patients.

详细描述

Low back pain is a multi-dimensional musculoskeletal condition resulting in discomfort and functional limitation, arising from lower lumbar region radiating towards posterior lower limb or anterior thigh, often resulting from numerous factors like mechanical, degenerative, neuropathic, inflammatory, infectious, neoplastic and psychological factors. One of the most prevalent association of low back pain is nerve irritation and poor neuromuscular coordination. According to nerve pathway and innervation pattern, the main constituents of lumbosacral plexus are sciatic and femoral nerves. Sciatic nerve arises from L4-S3 spinal nerve roots passing through the gluteal region and down the posterior thigh innervating hamstrings, gastrocnemius, soleus, tibialis posterior, flexor digitorum longus, flexor hallucis longus, fibularis longus and brevis. Whereas, femoral nerve originates from L2-L4 and supply along the anterior region of thigh musculature like quadriceps femoris, sartorius, pectineus.

Normal nerve function, reduced mechanical sensitivity, and relief of radiating symptoms are the main goals of neural mobilization. Complementary to this, there are numerous studies which shows the effects of Electrical Muscle Stimulation that reduces pain by maximizes neuromuscular control and activation, facilitates blood circulation and prevents muscular atrophy in low back pain patients.

According to study conducted in 2022 by Romero-Morales and colleagues in Spain, neural mobilization has great effect in management of pain and disability in musculoskeletal disorders. Another study done in Japan in 2023 has describe the efficacy of Neural Mobilization on Pain, Mobility, and Psychosocial Functioning of Patients.

Peripherally neural mobilization increases nerve conductivity and physiologically it changes central sensitization. With an eye towards maximizing functional recovery and pain relief, this comparative study evaluates the combined effects of nerve mobilization and Electrical Stimulation in treatment of Low Back Pain, which has emerging evidence from a study which is published in the journal of pain, USA in 2002 that explains the efficacy of Electrical stimulation with combined therapy .

Another number of studies has also been done explaining the effect of neural mobilization on low back pain one of which is published in Pakistan journal of medical and health sciences in 2022 concluding that sciatic nerve mobilization is an effective treatment for pain and disability in patients.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Double (Participant, Outcomes Assessor)

入排标准

年龄范围
20 Years 至 50 Years(Adult)
性别
All
接受健康志愿者
否

入选标准

  • •Age between 20-50 years
  • •Radiating pain pattern
  • •Muscular pain pattern
  • •Negative sensory and motor neural examination
  • •Patients with peripheral nerve sensitization were included if they were adults and had leg pain duration of < 3 months(8)
  • •VAS Score between 4 and 8
  • •Positive findings of tests like thigh thrust, Patrick's Faber test, Gaenslen's test, modified Trendelenburg's test and Slump test.

排除标准

  • •Pregnancy
  • •Post-partum females
  • •Serious spinal pathology
  • •Sensory and motor deficient
  • •History of back and lower extremity surgery
  • •Patients with contraindication to Electrical Stimulation
  • •Any serious kind of co-morbidities like malignancy, infections
  • •Any kind of disability

研究组 & 干预措施

Sciatic nerve mobilization with Electrical Muscle Stimulation

Other

Each patient will receive therapeutic sessions over 2 weeks (3 sessions per week), with total of 6 sessions. The repetition of mobilization will be 10 times for 2 sets with 2 minutes rest in between the sets. Electrical Muscle Stimulation (EMS) device was applied at a pulse frequency of 100 Hz. Placement of 2 surface electrodes will be used for stimulation over a session period of 15 minutes.

干预措施: Sciatic nerve mobilization with EMS (Other)

Femoral neural mobilization with Electrical Muscle Stimulation

Other

Each patient will receive therapeutic sessions over 2 weeks (3 sessions per week), with total of 6 sessions. The repetition of mobilization will be 10 times for 2 sets with 2 minutes rest in between the sets. Electrical Muscle Stimulation (EMS) device was applied at a pulse frequency of 100 Hz. Placement of 2 surface electrodes will be used for stimulation over a session period of 15 minutes.

干预措施: Femoral neural mobilization with EMS (Other)

结局指标

主要结局

Visual analog scale (VAS)

时间窗: 8 WEEKS

Pain intensity was further measured using the Visual Analog Scale (VAS), ranging from 0 mm (no pain) to 100 mm (worst imaginable pain). VAS scores were categorized as follows: 0-4 mm indicating no pain, 5-44 mm mild pain, 45-74 mm moderate pain, and 75-100 mm severe pain.21

次要结局

  • Goniometer for range of motion (ROM)(8 WEEKS)
  • Oswestry disability index (ODI)(8 WEEKS)
  • EuroQol 5 Dimension Questionnaire (EQ-5D)(8 WEEKS)

研究者

发起方
Shalamar Institute of Health Sciences
申办方类型
Other
责任方
Sponsor

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