Nutritional Risk for Hospitalized Patients With Neurology Disorders in China

Not yet recruiting

• Conditions: Neurological Disorder

• Registration Number: NCT06510712
• Lead Sponsor: Xuanwu Hospital, Beijing

Brief Summary

Neurology disorders are one of the major public health problems that seriously threaten human health. It often accompanied by various nutritional problems, which can aggravate the primary disease, lead to serious complications, prolong the hospitalization, lead to poor prognosis, and increase family and social economic burdens. According to the previous studies, the risk of malnutrition was approximately 58.5% of stroke patients, and 6% had moderate to severe malnutrition in China. Another study conducted in Beijing showed that the risk of malnutrition of elderly patients in the department of neurology was significantly higher than in other departments (28.5% vs. 26.4%). Strengthening nutritional supervision of patients with neurology disorders will benefit to improve patients' prognosis. Therefore, the aim of this study is to investigate the nutritional status of inpatients with neurology disorders in China, evaluate the impact of different nutritional status on patients' health outcomes, and establish a high-quality, standardized nutrition and health cohort database for neurology disorders.

Detailed Description

Not available

Study Timeline

• Status Verified: 2024-07
• Study First Submitted: 2024-07-14
• Study First Submitted QC: 2024-07-14
• Last Update Submitted: 2024-07-14
• Study First Posted: 2024-07-19
• Last Update Posted: 2024-07-19
• Study Start: 2024-09-01
• Primary Completion: 2026-06-01
• Study Completion: 2026-06-30

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 10000

Inclusion Criteria

1. Age ≥ 18 years;
2. The primary diagnosis was neurological disorders;
3. Written informed consent.

Exclusion Criteria

1. Life expectancy is < 3 months;
2. Researchers think other ineligible participant for the study.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
All-cause mortality	30 days	Mortality defined as all-cause mortality from inclusion to day 30

Secondary Outcome Measures

Name	Time	Method
Non-elective hospital readmission	30 days	Non-elective hospital readmission defined as non-scheduled hospital readmission after discharge from the index hospital stay to day 30
ICU admission	30 days	ICU admission defined as admission to the intensive care unit from the medical ward from inclusion to day 30
Major complications	30 days	Major complications defined as the following complications occurring from inclusion (i.e., not present at the time of inclusion) to day 30 I. Adjudicated nosocomial infection or abscess requiring antibiotic treatment II. respiratory failure with need for invasive or non-invasive ventilation III. major cardiovascular events including stroke, intracranial bleeding, cardiac arrest, myocardial infarction with and without invasive procedure and pulmonary embolism IV. acute renal failure (defined by 2x increase of baseline creatinine or new requirement of dialysis do to volume overload or electrolyte disturbance) V. gastro-intestinal events (hemorrhage, intestinal perforation)
length of in hospital days	30 days	Total length of in hospital days 30 days
Decline in functional status of 10% or more	30 days	decline in functional status of 10% or more from admission to day 30 measured by the Barthel's index.