Evaluation of the safety and feasibility of delivering human umbilical cord mononuclear cells (cbMNCs) via catheter to the proximal end of the lesion artery in patients with sub-acute stroke in the territory of the middle cerebral artery

Vice Chancellor for Research and Technology, Iran University of Medical Sciences0 个研究点目标入组 4 人开始时间: 待定最近更新: 2018年2月22日

适应症

试验速览

暂无简介。

•age: 18-75;
•MRI or CT scan with infarct in middle/anterior cerebral artery without hematoma; ischemic
•storke with 7 -30 days before;
•Glasgow Coma Scale score >8;
•BI score of =50, National
•Institute of Health stroke scale
•(NIHSS) score of =7; inability to raise arms to 90 degrees; stable condition more than 48 hours,
•normal body temperature;
•normal blood pressure with mean
•arterial pressure<125 mmHg
•(with systolic blood pressur>90
•mmHg); normal blood
•sugar<200 mg/dl; normal
•urea/electrolyte. Exclusion
•criteria: lacunar syndrome;
•intubation; posterior circulation
•stroke; morbidity likely to limit
•survival to less than 3 years;
•pre-stroke disability leading to
•dependence on others for activity
•of daily living; inaccessibility for
•follow up; allergy to local
•anesthetic; unwillingness to
•provide written informed
•consent; symptoms suggestive of
•acute cardiac; hepatic or renal
•disease; pregnancy; HIV
•positivity; participation in any
•other trial; poor access vessel
•angiography; Fever.

发起方

Vice Chancellor for Research and Technology, Iran University of Medical Sciences