跳至主要内容
临床试验/CTRI/2025/04/085331
CTRI/2025/04/085331尚未招募2 期

A Comparative Clinical Study on the Efficacy of Virechana and Doshaharana Guna of Patolamooladi Kashaya in Ekakushta w s r to Psoriasis

Parikshitha K R1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2025年5月20日最近更新:

试验速览

阶段
2 期
状态
尚未招募
发起方
入组人数
40
试验地点
1
主要终点
to assess the improvement in signs and symptoms of psoriasis using pasi score and other parameters in 2 treatment modalities, 2weeks

研究概览

简要总结

the skin, a multifunctional organ, acts as both a protective shield and a sensory

interface, essential for regulating temperature and detecting stimuli. skin is the largest

organ of the body which guards various underlying muscles, bones, ligaments and

internal organs 1 .

ekakushta is a type of a kushta which is kapha vata pradhana. symptoms may

include aswedanam, mahavastu and mathyashakalopamam 2 . kushta is a kleda

pradhana, bahu doshaja, deergha roga involving saptako dravya sangraha and is

considered one among the ashta mahagada. when one consumes etiological factors

mentioned in samhitas, tridosha (vata, pitta and kapha) gets vitiated and

contaminates skin (twak), blood (rakta), muscle (mamsa) and lymph (lasika) which

causes kushta 3 . kushta is categorized into 2main types: maha kushta and kshudra

kusta. ekakushta is a type of kshudra kushta. psoriasis, a prevalent dermatological

condition affecting around 2-3% of the global population, manifests as erythematous

papule and plaques covered by silvery scales, often accompanied by itching and is

mediated by the immune system. it may begin at any age, but commonly starts in

adulthood 4 . with psoriasis being linked to ekakustha, in this current study all forms of

psoriasis are being examined due to their overlapping symptoms with ekakustha.

as mentioned in our samhitas, the line of treatment of most of the skin

diseases are shodhana and shamana 5 . shodhana facilitates the expulsion of vitiated

doshas from the body. acharya charaka highlight the virechana karma in kushta

chikitsa 6 . according to acharya sushrutha’s teaching in kushta chikitsa he advises

virechana karma once in a month 7 . in today’s fast-paced world, its crucial to find

efficient treatment options that save time for individuals dealing with various

conditons, since persuading individuals to undergo shodhana can be challenging, an

effort is being made to seek an alternative method for treatment, such as

patolmoolaadi kashaya the recommendation for the patient involves preparing

kashaya by boiling kwatha churna and taking it on an empty stomach for 6 days,

which do doshaharana 8 . in this current study, the application of virechana and

doshaharana guna of patolamooladi kashaya has been implemented among

individuals diagnosed with ekakushta w.r.s psoriasis.

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • subjects presenting with clinical features of psoriasis.
  • subjects presenting with the lakshanas of ekakushta.
  • subjects of either gender in between age group of 18 to 60 years.
  • subjects fit for virechana karma.

排除标准

  • subjects with any systemic diseases that may interfere with the course of treatment.

结局指标

主要结局

to assess the improvement in signs and symptoms of psoriasis using pasi score and other parameters in 2 treatment modalities, 2weeks

时间窗: to assess the improvement in signs and symptoms of psoriasis using pasi score and other parameters in 2 treatment modalities, 2 weeks

次要结局

未报告次要终点

研究者

发起方
Parikshitha K R
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Parikshitha K R

Sri Kalabyraveshwara Swamy Ayurvedic Medical College Hospital & Research Centre

研究点 (1)

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