Monitoring of regional ventilation distributions prior to and after chest physiotherapy in pediatric patients with pulmonary diseases - a feasibility study using the electrical impedance tomography.

Recruiting

• Conditions: Pediatric patients with acute and chronic pulmonary diseases (bronchitis, bronchopneumonia, pneumonia, atelectasis, congenital pulmonary malformations [diaphragmatic hernia, sequester, cystic malformations, pulmonary hypoplasia, scoliosis, pectus excavatum, etc.], congenital disorders of lung clearance [cystic fibrosis, ciliary dyskinesia]).; J18.0; P23; J20; Q79.0; Q33.0; E84; Acute bronchitis; Congenital diaphragmatic hernia; Congenital cystic lung

• Registration Number: DRKS00032506
• Lead Sponsor: niklinikum Bonn, Eltern-Kind-Zentrum, Klinik für Neonatologie und Pädiatrische Intensivmedizin

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2023-08-17
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Newborns, infants, small children, schoolchildren with the need for chest physiotherapy in the context of an acute or chronic pulmonary disease
• Weight =3.5 kg and/or chest circumference =36cm
• Parental consent to study participation

Exclusion Criteria

- preterm birth <37 weeks of gestational age
- Mechanical ventilation
- Pediatric patients receiving palliative care
- Lack of parental consent

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Detection of an improvement of the ventilation distribution after chest physiotherapy according to at minimum one EIT-Index measured with the PulmoVista 500 tomograph (Fa.Dräger): 1) Global-Inhomogeneity (GI) Index, 2) End-Expiratory Lung Impedance (EELI), or 3) mean Center-of-Ventilation (CoV).

Secondary Outcome Measures

Name	Time	Method
1) The electrical impedance tomography (EIT) measurement does not have a negative impact on the chest physiotherapeutich treatmen.<br><br>2) The electrical impedance tomography (EIT) measurement provides results with a high signal quality (delta impedance) across all lung fields in children before and after chest physiotherapy.<br><br>3) The electrical impedance tomography (EIT) gives children (>2 years, due to cognitive capability) a visual impression of the inhalation and exhalation and increases in a playfull way the motivation of the patient during the chest physiotherapy.