Raloxifene in men with chronic schizophrenia
- Conditions
- schizophrenia.schizophrenia
- Registration Number
- IRCT201211211556N47
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Male
- Target Recruitment
- 46
Inclusion Criteria:1-Diagnosis of Schizophrenia based on DSM- IV criteria;2- Minimum Score of 60 on Positive and Negative Scale 3- Age between 18-55;4-male sex 5- chronic Schizophrenia- duration of the disorder more than 2 years; ; 6-Minimum score of 20 in negative suscore
1-any other mental disorder on axis I; 2-Any serious medical or neurological problem; 3- IQ less than 70;4- Substance dependence during the last 6 months(except for nicotine and caffeine) 5-receiving oral antipsychotic medications during the last week or receiving any depot antipsychotic medication during the last month; ;6-receiving ECT during the last 14 days, 7-Endocrine abnormality; 8-hepatic and renal disease 9- history of thrombosis and embolism 10 history of abnormal bleeding 11- CVA
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Severity of schizophrenia. Timepoint: Baseline and weeks 2-4-6-8 after beginig of treatment. Method of measurement: Positive and Negative Syndrome Scale (PANSS).
- Secondary Outcome Measures
Name Time Method