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Clinical Trials/CTRI/2019/05/018900
CTRI/2019/05/018900
Completed
Phase 3

A comparison of the effectiveness of supplementary intraligamentary injectionsof tramadol and lignocaine in emergency root canal treatment of adultmandibular molars with irreversible pulpitis: a randomized control trial

nil0 sites34 target enrollmentTBD

Overview

Phase
Phase 3
Intervention
Not specified
Conditions
Not specified
Sponsor
nil
Enrollment
34
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
January 2, 2020
Last Updated
4 years ago
Study Type
Interventional

Investigators

Sponsor
nil

Eligibility Criteria

Inclusion Criteria

  • 1\. Healthy adults (ASA\-I or ASA\-II), aged between 18 â?? 65 years, who signed consent form.
  • 2\. Symptomatic irreversible pulpitis of the mandibular first or second molar.
  • a) The patients who have pain in a mandibular molar (visual analog scale \>54\) with prolonged response to cold testing (lingering pain for more than 45 seconds).
  • b) Absence of any periapical radiolucency on a periapical radiograph (except for a widened periodontal ligament of no more than 0\.75â??1 mm and no pain on percussion).
  • 3\. Vital teeth with no history of previous root canal therapy.
  • 4\. Ability to understand the consent forms and the pain record scales.

Exclusion Criteria

  • 1\. A known allergy, sensitivity, or contraindications to any local anaesthetics or opioids. Those patients who show any abnormal reaction to the test dose of the drugs.
  • 2\. History of seizures, systemic diseases such as diabetes, uncontrolled hypertension, acute or severe bronchial asthma, significant respiratory depression, decreased renal or liver function.
  • 3\. Pregnancy or lactation.
  • 4\. History of narcotics or psychotic drugs, patients who had taken NSAIDs or sedatives within 24 hours before the root canal treatment.
  • 5\. Patients experiencing pain in more than 1 mandibular molar.
  • 6\. During the procedure, patients will be excluded if lip numbness is not achieved after the inferior alveolar nerve block.

Outcomes

Primary Outcomes

Not specified

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