ACTRN12613001036707
Completed
N/A
In patients undergoing a total knee replacement, does adding ketamine to a morphine patient controlled analgesia (PCA) lead to improved analgesia as measured by VNRS? A randomised, prospective, double-blinded study.
Yoon Leng Ooi0 sites530 target enrollmentSeptember 18, 2013
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Yoon Leng Ooi
- Enrollment
- 530
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Elective patients undergoing a Total Knee Replacement
- •18 years or older
- •Would be able to understand the use of a Patient Controlled Analgesia (PCA) system
Exclusion Criteria
- •An allergy to morphine or ketamine
- •Patient inability to use a PCA
- •Pre\-existing neurological or psychiatric illnesses
- •Evidence of severe cardiovascular, renal, hematologic or hepatic disease
- •Patients unsuitable for the study’s standardised anaesthetic technique
- •Patients requiring other analgesic drugs or regional techniques which may affect the appreciation of pain
- •Alcohol and opioid dependent patients
- •Patients with a history of chronic pain
Outcomes
Primary Outcomes
Not specified
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