Effect of Smoking Cessation on Non-surgical Periodontal Therapy
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- University of Sao Paulo
- Enrollment
- 177
- Primary Endpoint
- Change in Clinical Attachment Level (millimeters) after 24 months
Study Overview
Brief Summary
The aim of this prospective study is to verify the efficacy of smoking cessation on non-surgical periodontal therapy in adult subjects with chronic periodontitis.
Smokers that were willing to quit received periodontal treatment and concurrent smoking cessation therapy. Periodontal maintenance was performed every 3 months. A calibrated examiner, blinded to smoking status, assessed periodontal status, gathered demographic and behavioural information with a structured questionnaire and measured air carbon monoxide concentration measurements.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •subjects were willing to stop smoking
- •>10 teeth
- •periodontitis (30% or more of their teeth with proximal CAL ≥ 5 mm
Exclusion Criteria
- •systemic conditions considered as risk factors for periodontal disease,
- •periodontal therapy in the last 6 months
- •continuous systemic use of anti-inflammatory or steroidal drugs
Arms & Interventions
Adjunctive smoking cessation
non-surgical periodontal therapy and concurrent smoking cessation therapy
Intervention: Smoking cessation therapy (Behavioral)
Adjunctive smoking cessation
non-surgical periodontal therapy and concurrent smoking cessation therapy
Intervention: Non-surgical periodontal therapy (Procedure)
Outcomes
Primary Outcomes
Change in Clinical Attachment Level (millimeters) after 24 months
Time Frame: baseline and 24 months
Secondary Outcomes
- Change in Gingival recession (millimeters) after 24 months(baseline and 24 months)
- Change in Pocket depth (millimeters) after 24 months(baseline and 24 months)
- Change in bleeding on probing (percentage of sites with bleeding) after 24 months(baseline and 24 months)
- Change in visible plaque (percentage of sites with visible plaque) after 24 months(baseline and 24 months)
Investigators
Claudio Mendes Pannuti
Associate Professor
University of Sao Paulo