At-home Transcranial Alternating Current Stimulation During Multitasking
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 47
- 试验地点
- 1
- 主要终点
- Multitasking Performance Cost (Neuroracer Performance Change From Baseline)
研究概览
简要总结
The goal is to replicate in-lab results from transcranial alternating current stimulation (tACS) with at-home tACS.
详细描述
Participants will be assessed in-lab on multitasking and sustained attention abilities. Participants will be sent home with a tACS device to be used at-home for five days while engaged in a multitasking paradigm that is different from the multitasking outcome measure used pre/post tACS. After the at-home stimulation is complete, participants return to UCSF for a final in-lab assessment of multitasking and sustained attention ability.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •English speaking
- •Grade 12 or more education
- •Normal or corrected to normal vision and hearing
- •Ability to complete cognitive tasks
- •Ability to cooperate and comply with all study procedures
- •Ability to tolerate tACS
排除标准
- •Neurological or psychiatric disorders
- •Family history of epilepsy
- •History of seizures
- •Prior head trauma
- •Implanted electronic devices (e.g., pacemaker)
- •Taking psychotropic medication
- •Taking anti-depressants or anti-anxiety medication
- •Substance abuse
- •Color blind
- •Macular degeneration
- •Amblyopia
- •Strabismus
研究组 & 干预措施
Verum Stimulation
This group will receive 6-Hz tACS
干预措施: Transcranial alternating current stimulation (Device)
Frequency Control
This group will receive 1-Hz tACS
干预措施: Transcranial alternating current stimulation (Device)
结局指标
主要结局
Multitasking Performance Cost (Neuroracer Performance Change From Baseline)
时间窗: Pre-tACS and post-tACS (1 week later)
Assessment of multitasking ability using change from baseline scores in d' cost (metric of discriminability). Discrimination performance (d') was measured for each participant by comparing hit (correct responses to target signs) rates and false alarm (responses to non-targets) rates and calculated as d' = Z (hits) - Z (false alarms). d' cost was then calculated as the ratio of d' during single task target discrimination task to multitask target discrimination, expressed as percentage cost.
Single Task Performance Change
时间窗: Pre-tACS and post-tACS (1 week later)
Discrimination performance (d') was measured during single task performance for each participant by comparing hit (correct responses to target signs) rates and false alarm (responses to non-targets) rates and calculated as d' = Z (hits) - Z (false alarms). Performance data was collected during the single task condition.
Multitask Performance Change
时间窗: Pre-tACS and post-tACS (1 week later)
Discrimination performance (d') was measured while multitasking for each participant by comparing hit (correct responses to target signs) rates and false alarm (responses to non-targets) rates and calculated as d' = Z (hits) - Z (false alarms). Performance data was collected during the multitask condition.
次要结局
- Continuous Performance Test RT Change (Test of Visual Attention / Sustained Attention)(Pre-tACS and post-tACS (1 week later))
- Continuous Performance Test RTV Change (Test of Visual Attention / Sustained Attention)(Pre-tACS and post-tACS (1 week later))