Early Renal Replacement Therapy in COVID 19 Patients With AKI Does it Improve the Outcome?

Not Applicable

Completed

• Conditions: Multi Organ Failure
• Interventions: Procedure: haemodialysis

• Registration Number: NCT05274685
• Lead Sponsor: Sohag University

Brief Summary

patients will be divided into two equal groups, each group including 50 adult patients with a confirmed diagnosis of covid, patients with acute kidney injury, the first group will be treated with early hemodialysis, second group will be conservative until there is an urgent need for dialysis

Detailed Description

Not available

Study Timeline

• Study Start: 2021-06-01
• Primary Completion: 2021-12-01
• Study Completion: 2022-01-01
• Status Verified: 2022-02
• Study First Submitted: 2022-03-09
• Study First Submitted QC: 2022-03-09
• Last Update Submitted: 2022-03-09
• Study First Posted: 2022-03-10
• Last Update Posted: 2022-03-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• adult patients (≥18 years old) with confirmed severe acute respiratory syndrome coronavirus 2 infections admitted to the ICU.

Exclusion Criteria

• •Malignancy.

  • Immuno-deficiency diseases.
  • Chronic diabetic, cardiac and hypertensive patients
  • autoimmune diseases.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
covid positive with acute kidney injury under conservative management	haemodialysis	-
covid positive with acute kidney injury receiving early renal replacement	haemodialysis	-

Primary Outcome Measures

Name	Time	Method
reduction of Sequential Organ Failure Assessment Score	2 weeks	prevention of multi-organ failure associated with covid including respiratorym circulatory, liver and renal failure

Trial Locations

Locations (1)

Faculty of Medicine, Sohag University; 🇪🇬 Sohag, Egypt