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临床试验/NCT02425020
NCT02425020已完成不适用

Effects of Meat Protein Administration on Body Composition, Strength, Muscle Structure and Markers of Muscle Damage and Health in Athletes

University of Greenwich0 个研究点目标入组 30 人开始时间: 2015年2月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
30
主要终点
Body composition

研究概览

简要总结

The aim of this project is to investigate the potential benefits of combining a new protein meat hydrolysates extract with a regular resistance training programme on (a) body composition (b) performance (c) muscle structure (d) general markers health and immunity in athletes. As a second objective the investigators will analyse potential differences obtained from the ingestion of the new hydrolysates meat protein extract compared to the ingestion of others commercially available protein sources such as whey or casein.

详细描述

This investigation involves a 8 weeks randomised, balanced, double blind parallel group between-subjects design aimed to analyse the effects of combining exercise and a post exercise nutrition strategy (hydrolysates meat protein, whey protein or a isocaloric only carbohydrate placebo) on training outcomes, markers of immunity and health after a period of regular training and feeding intervention. Participants will be divided in three-treatment groups 1) Hydrolysed meat-protein (MEAT); 2) Whey (W) and 3) non-protein iso-energetic placebo (CHO). Once considered eligible for the study, and after an initial familiarisation period and baseline tests, participants will be randomly assigned to one of the intervention groups: MEAT; W and CHO. Each group will follow a 8-week periodised resistance training intervention combined with one of the three specific supplementation treatments (MEAT, W or CHO). Measurements of general markers of health, immunity, body composition, muscle structure and performance will be determined before and after the training intervention.

Once informed consent and health history have been obtained, after the baseline Assessment (t1), participants will divided into three similar profile groups, matched by body mass, age, sex and performance. 1) The meat protein group (MEAT n=10) that will take 250 ml of orange juice mixed with 20g of hydrolysates meat protein powder and water 2) The whey group (n=10) will take 20 g of whey intact isolate powder mixed with 250 ml of orange juice and water 3) the contrast group (P n=10) that will take an iso-energetic non-protein, only carbohydrate (maltodextrin) placebo.

Participants: Thirty participants, recruited from the University Campus, will take part in the project. After being informed of all risk, discomforts, and benefits involved, participants will sign a written informed consent regarding their participation.

Intervention Familiarization period: Participants will undertake 3 sessions of familiarization (1 weeks). A qualified strength and conditioning coach will control and assists participants in order to guarantee a correct execution of the selected exercise. All participants will be instructed about the appropriate use of the Rate of Perceived Exertion (0-10) scale to control the load and training intensity.

Resistance Training: The resistance-training program will be designed to increase strength and mass of all major muscle groups. The program will be undertaken on three non-consecutive days per week, under the supervision of strength and conditioning coaches, preferable Strength and Conditioning master students. Training workout will be performed during the afternoon (between 3pm and 6pm) with at least 48 hours between sessions.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)

入排标准

年龄范围
18 Years 至 45 Years(Adult)
性别
All
接受健康志愿者
是

入选标准

  • •regularly trained athletes,
  • •aged 18 to 45 years old,
  • •minimum 3 months of experience in resistance training exercise,
  • •volunteers,

排除标准

  • •any musculoskeletal injuries, metabolic conditions, or diseases;
  • •use of medications, smoking, and nutritional supplements known to affect physical performance, muscle damage or recovery process (e.g., creatine, whey protein, and amino acids) within 6 weeks prior to the start of the study.

研究组 & 干预措施

Meat protein

Experimental

Post workout (training days) or breakfast (non training days) 20g of meat protein mixed with 250ml of orange juice and water

干预措施: Meat Protein (Dietary Supplement)

Carbohydrate

Active Comparator

Post workout (training days) or breakfast (non training days) maltodextrin mixed with 250ml orange juice and water

干预措施: Carbohydrate (Dietary Supplement)

Whey Protein

Experimental

Post workout (training days) or breakfast (non training days) 20g of whey protein isolate mixed with 250ml of orange juice and water

干预措施: Whey protein (Dietary Supplement)

结局指标

主要结局

Body composition

时间窗: 8 weeks

Fat Free mass and Fat Mass.

次要结局

  • Analysis of total cholesterol(8 weeks)
  • Analysis of Aspartate amino transferase(8 weeks)
  • Analysis of glycaemia(8 weeks)
  • Analysis of LDL,cholesterol(8 weeks)
  • Muscle damage marker(8 weeks)
  • Muscle Structure(8 weeks)
  • Analysis of HDL, cholesterol(8 weeks)
  • Analysis of Alanine amino transferase(Pre and post 8 weeks intervention programme)
  • Analysis of Triglycerides(8 weeks)
  • Analysis of Urea(8 weeks)
  • Analysis of Uric acid(8 weeks)
  • Immune system (Analysis of Antimicrobial peptides)(8 weeks)
  • Maximal Strength performance(8 weeks)
  • Power performance (jump test on force plate and maximal power at 50% 1RM bench press)(8 weeks)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Fernando Naclerio

Principal Lecturer

University of Greenwich

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