Immediate Suboptimal Result of Mitral Valve Repair: Late Implications in a Matched Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 141
- 试验地点
- 1
- 主要终点
- Mortality
研究概览
简要总结
Mitral valve regurgitation is a pathology affecting the left atrioventricular valve, conditioning the loss of the normal unidirectionality of the atrioventricular flow and therefore volumetric and pressure overload of the left heart chambers. In industrialized countries, the most common etiology of mitral regurgitation is degenerative mitral disease.
Mitral valve repair surgery represents the gold standard for the treatment of severe degenerative mitral regurgitation. The expected optimal result would be the absence of residual post-procedural mitral regurgitation, even if it is not uncommon to obtain a valve with residual regurgitation of a mild degree. In some cases, for various reasons (technical difficulties, long aortic clamping time, advanced age, high pre-operative surgical risk), a suboptimal result is accepted, i.e. a post-procedural residual mitral regurgitation of even a moderate degree ( 0, 1+, or 2+/4+).
The aim of the present study is to evaluate the late clinical and echocardiographic implications of suboptimal mitral valve repair with a paired-data cohort study
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Study group:
- •presence of severe degenerative mitral regurgitation treated by mitral valve repair between 2006 and 2013;
- •presence of moderate residual mitral regurgitation at discharge.
- •Control group:
- •presence of severe degenerative mitral regurgitation treated by mitral valve repair between 2006 and 2013;
- •presence of residual mitral regurgitation of at least mild grade at discharge.
排除标准
- 未提供
结局指标
主要结局
Mortality
时间窗: through study completion, a minimum of 6 years
次要结局
未报告次要终点
研究者
Michele De Bonis
Chief of Cardiac Surgery of Advance and Research Therapies
Ospedale San Raffaele
