Effectiveness of smartphone-based mobile application on medication adherence in patients receiving growth hormone therapy-An exploratory observational study. (GTL-App)
Not Applicable
- Conditions
- Short statue caused by -Growth hormone (GH) deficiency -Turner syndrome -Small for gestational age
- Registration Number
- JPRN-UMIN000035997
- Lead Sponsor
- Department of Pediatrics, Nihon University Hospital
- Brief Summary
This study enrolled 60 children with short stature from 28 Japanese medical institutions and analyzed 57 of them. The median and mean adherence rates after 24 wk of observation were 96% and 93%, respectively. Although adherence rates were significantly lower from wk 16 to wk 20 than from wk 1 to wk 4, cumulative adherence rates remained high throughout the observation period. The questionnaire analysis revealed that most patients actively used the application.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Not provided
Exclusion Criteria
-Contraindications for GH therapy. eg, Diabetes, malignancy, (possible) pregnancy. -Not supposed to be able to answer the questionnaire properly, eg, unable to read. -Judgement of physicians.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Medication adherence of patients during 24 weeks of observation period.
- Secondary Outcome Measures
Name Time Method -Patients characteristics at registration. -Time course change in medication adherence. -Nonadherence-free survival. -Questionnaire on GH therapy. -Questionnaire on mobile application. -Factors affecting adherence to GH therapy. -Exploratory analysis of application log data.