Comparison Of Effects Of Pregabalin and Clonidine On Pain, Sedation and Recovery From General Anesthesia After Laparoscopic Hysterectomy

Completed

• Conditions: Menopausal and other perimenopausal disorders,

• Registration Number: CTRI/2020/12/029541
• Lead Sponsor: Institute of Medical Sciences And SUM Hospital

Brief Summary

A comparative study of preemptive oral pregablin (75mg) and oral clonidine (150 mcg) to assess the degree of analgesia via VAS score, level of sedation via Ramsay sedation scale and the recovery via Modified Aldrete score in female patients posted for laparoscopic hysterectomy after the end of the surgery.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-12-15
• Last Update Posted: 2022-10-02

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 90

Inclusion Criteria

• Patients belonging to ASA Grade-I status 2.
• Patients posted for elective laparoscopic hysterectomy.

Exclusion Criteria

• Refusal of the patient to participate in the study 2.
• Patients belonging to ASA Grade II/III/IV status 3.
• Patients with any chronic pain syndrome under treatment with any GABAergic drugs 5.
• Patients in whom laparoscopy was converted to laparotomy.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Degree of pain assessed by 10-point Visual Analogue Scale (VAS)	At baseline, 1, 2, 4, 6, 12 and 24 hours respectively.

Secondary Outcome Measures

Name	Time	Method
Degree of Sedation measured by Ramsay Sedation Scale(RSS)	At baseline, 6, 12 and 24 hours respectively.
Recovery measured using Modified Aldrete score	Before discharge to ward from the recovery room

Trial Locations

Locations (1)

IMS and SUM Hospital; 🇮🇳 Khordha, ORISSA, India

IMS and SUM Hospital

🇮🇳Khordha, ORISSA, India

Dr Eesha Banerjee

Principal investigator

7501724995

eesha5banerjee70@gmail.com