The effect of Autologous Serum Therapy in Chronic Spontaneous Urticaria
Not Applicable
- Conditions
- Chronic spontaneous urticaria.Other urticaria
- Registration Number
- IRCT20180113038328N1
- Lead Sponsor
- Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Symptoms lasting more than 6 weeks
Negative Prick test for oral and inhalatory allergens
Aged higher than 15 years
Normal laboratory result for CBC/diff - S/E - U/A-LFT-HBsAg-BUN-Cr-ESR-CRP-CH50-ANA-IgE and anti-Helicobacter pylori tests
Exclusion Criteria
Physical urticaria
Allergic and drug urticaria
Vasculitis urticaria
Cortisone and immunosuppressive use over the past 6 weeks (other than antihistamines)
Pregnancy
Lactation
Other systemic diseases.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Spontaneous chronic urticaria is a qualitative variable with clinical parameters and cytokines is a of quantity Variable that is measured with PCR. Timepoint: Before and after treatment, as well as 4 weeks after the completion of treatment. Method of measurement: Urticaria total severity score (TSS) ,dermatology quality of life index (DLQI),Real-time-PCR.
- Secondary Outcome Measures
Name Time Method