An Open-label Pilot Study to Learn How the Phenotypical Characteristics of Woebot Users Are Related to Clinical Outcomes

Patient Health Questionnaire

时间窗: Change from Baseline to Mid-Intervention at Week 4; change from Baseline to Post-intervention at Week 8; change from Mid-Intervention at Week 4 to Post-intervention at Week 8

Measure of depression. An 8-item self-report questionnaire where total scores range from 0 to 24, with higher scores indicating greater levels of depression

Client Satisfaction Questionnaire (CSQ-8)

时间窗: Post-intervention at Week 8

An 8-item measure used to assess client's satisfaction with treatment.Total scores range from 8-32, with high scores indicating greater satisfaction with the treatment.

Working Alliance Inventory (WAI)

时间窗: Change from Day 3 to Mid-Intervention at Week 4; change from Day 3 to Post-intervention at Week 8; change from Mid-Intervention at Week 4 to Post-intervention at Week 8

Measure of working alliance. A measure of therapeutic alliance that assesses three key aspects of the therapeutic alliance: (a) agreement on the tasks of therapy, (b) agreement on the goals of therapy and (c) development of an affective bond. Total scores range from 12-60, with higher scores indicating greater alliance. The present study utilized the validated 12-item Short-Revised version (WAI-SR) with minor changes to language, replacing "therapist" with "Woebot".

Mental Health Self-Efficacy Scale (MHSES)

时间窗: Change from Baseline to Mid-Intervention at Week 4; change from Baseline to Post-intervention at Week 8; change from Mid-Intervention at Week 4 to Post-intervention at Week 8

Six items assess confidence in managing stress, depression, and anxiety, and are scored on a 10 point Likert scale (from 1, not at all confident to 10, very confident). Ratings across the 6 items are summed for an overall measure of MHSES (range 10 to 60), with higher scores indicating more self-efficacy. This measure is included as a way to capture an individual's confidence that they can successfully manage their mental health concerns.

Patient-Reported Outcomes Measurement Information System Global Health (PROMIS)

时间窗: Change from Baseline to Mid-Intervention at Week 4; change from Baseline to Post-intervention at Week 8; change from Mid-Intervention at Week 4 to Post-intervention at Week 8

Ten items used to assess five core domains of health (physical function, pain, fatigue, emotional distress, and social). Total scores range from 5-50, where greater scores represent the best health and functioning.

Work Productivity and Activity Impairment (WPAI)

时间窗: Change from Baseline to Mid-Intervention at Week 4; change from Baseline to Post-intervention at Week 8; change from Mid-Intervention at Week 4 to Post-intervention at Week 8

The WPAI measures presenteeism, absenteeism, work productivity loss for the currently employed, and activity impairment. WPAI outcomes are expressed as impairment percentages, with higher numbers indicating greater impairment and less productivity

App engagement metrics

时间窗: Baseline to Post-intervention at Week 8

Data tracking mobile application use, including conversational interactions with Woebot and patterns of engagement over time, will be collected throughout the duration of treatment (8-weeks).

Brief Resilience Questionnaire (BRS)

时间窗: Change from Baseline to Mid-Intervention at Week 4; change from Baseline to Post-intervention at Week 8; change from Mid-Intervention at Week 4 to Post-intervention at Week 8

The BRS is a measure used to assess a person's ability to bounce back or recover after experiencing a stressor. Total scores range from 1 (low resilience) to 5 (high resilience).

Perceived Stress Scale (PSS)

时间窗: Change from Baseline to Mid-Intervention at Week 4; change from Baseline to Post-intervention at Week 8; change from Mid-Intervention at Week 4 to Post-intervention at Week 8

The PSS is a 10-item tool to assess individual levels of stress in the past month. Total scores range from 0 (no stress) to 40 (very high levels of stress).

Toronto Alexithymia Scale (TAS)

时间窗: Change from Baseline to Mid-Intervention at Week 4; change from Baseline to Post-intervention at Week 8; change from Mid-Intervention at Week 4 to Post-intervention at Week 8

The TAS-20 is an instrument that measures alexithymia, or difficulty with identifying and describing emotions and focusing attention externally. Total scores range from 20-100, with with low levels of alexithymia indicative of high levels of emotional self-awareness and vice versa.

Burnout

时间窗: Change from Baseline to Mid-Intervention at Week 4; change from Baseline to Post-intervention at Week 8; change from Mid-Intervention at Week 4 to Post-intervention at Week 8

Single-item question to measure burnout on a scale from 1-5, where 5 is feeling completely burned out to the point change is needed.

Generalized Anxiety Disorder Questionnaire

时间窗: Change from Baseline to Mid-Intervention at Week 4; change from Baseline to Post-intervention at Week 8; change from Mid-Intervention at Week 4 to Post-intervention at Week 8

Measure of anxiety. A 7-item brief self-report questionnaire, where total score range is between 0-21, with higher scores indicate greater levels of anxiety.