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Clinical Trials/NCT05560243
NCT05560243
Completed
Not Applicable

Development, Implementation, and Evaluation of a Tobacco Cessation Intervention Tailored to Patients Living With HIV (PLWH) in Brazil: A Feasibility Study

University of Alabama at Birmingham1 site in 1 country56 target enrollmentSeptember 1, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
HIV Infections
Sponsor
University of Alabama at Birmingham
Enrollment
56
Locations
1
Primary Endpoint
Number of Participants With a 7-day Prevalence Abstinence of Tobacco Use
Status
Completed
Last Updated
last year

Overview

Brief Summary

The overall goal of this feasibility study is to make adaptations to these evidence-based approaches in collaboration with PLWH and health care providers working with this population, and develop, implement, and evaluate the feasibility and scalability of a theory-based, culturally relevant tobacco cessation intervention for PLWH receiving care through the public health system in a southern town in Brazil (Londrina). This proposal will focus on the intervention development, pretesting, and feasibility testing. The primary outcome will be a 7-day point prevalence abstinence (defined as no tobacco use in the past 7 days and verified through measurement of salivary cotinine and exhaled carbon monoxide levels) at 6-month follow-up. We will also conduct detailed treatment fidelity and scalability assessments (acceptability, feasibility, potential reach and adoption, alignment with the strategic context) to inform a full-scale efficacy trial.

Detailed Description

This study aims at developing and examining feasibility and scalability of a theory-based, culturally relevant tobacco cessation intervention for PLWH receiving care through the public health system in a southern town in Brazil. It consists of three phases: formative assessments with patients and health care providers to inform relevant components of the intervention, pretesting of the intervention components, and pilot testing of the intervention (feasibility).

Registry
clinicaltrials.gov
Start Date
September 1, 2021
End Date
August 31, 2023
Last Updated
last year
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Isabel Scarinci

Professor

University of Alabama at Birmingham

Eligibility Criteria

Inclusion Criteria

  • PLWH (that is, patients with a confirmed HIV diagnosis) receiving care at the reference center in Londrina
  • 18 years of age and older; (c) smoke at least 5 cigarettes (industrialized or hand-rolled) per day Smoked within the past seven days.
  • No intent to move from the area served by reference center in Londrina within the next 12 months.

Exclusion Criteria

  • History of hypertension
  • History of angina
  • History of asthma
  • On medication for depression.

Outcomes

Primary Outcomes

Number of Participants With a 7-day Prevalence Abstinence of Tobacco Use

Time Frame: 6-month follow-up

7-day point prevalence abstinence (defined as no tobacco use in the past 7 days and verified through measurement of salivary cotinine and exhaled carbon monoxide (CO) levels) at 6-month follow-up.

Secondary Outcomes

  • Participants With Tobacco Use Abstinence Based on Salivary Cotinine at 7-month Follow-up.(7 months)

Study Sites (1)

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