In Vitro Maturation With in Vitro Fertilization (IVF) Compared to Mild in Vitro Fertilization

Not Applicable

Suspended

• Conditions: Infertility
• Interventions: Procedure: In vitro maturation and in vitro fertilization; Procedure: Low doses of gonadotropin stimulation.

• Registration Number: NCT00867763
• Lead Sponsor: Batzofin Fertility Services

Brief Summary

Methods of infertility treatment may involve in vitro fertilization or IVF. Though effective, IVF is complex and expensive. Methods using no gonadotropin hormone stimulation of the ovaries are being compared to mild stimulation doses. The goal of the research is to determine which of these if more suitable as a low cost approach for varying individual patients.

Detailed Description

Low cost environment is utilized, but fees are charged.

Study Timeline

• Status Verified: 2009-03
• Study Start: 2009-03
• Study First Submitted: 2009-03-23
• Study First Submitted QC: 2009-03-23
• Study First Posted: 2009-03-24
• Last Update Submitted: 2010-08-10
• Last Update Posted: 2010-08-11
• Primary Completion: 2011-12
• Study Completion: 2012-06

Recruitment & Eligibility

• Status: SUSPENDED
• Sex: Female
• Target Recruitment: 1440

Inclusion Criteria

• Under age 42 female, normal uterine cavity, BMI 18-34kg/m2,

Exclusion Criteria

• Donor eggs, donor sperm, myoma over 5 cm
• Current hydrosalpinx, abnormal uterine cavity.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
IVM	In vitro maturation and in vitro fertilization	Early egg retrieval, in vitro maturation, then IVF
Mild IVF	Low doses of gonadotropin stimulation.	Mild gonadotropin and conventional IVF

Primary Outcome Measures

Name	Time	Method
Cost effectiveness	two years

Secondary Outcome Measures

Name	Time	Method
Ongoing pregnancy rates per cycle	3 months

Trial Locations

Locations (2)

Batzofin Fertilty Services; 🇺🇸 New York, New York, United States

BFS; 🇺🇸 NY, New York, United States