NCT00414739Unknown1 期
Testing of Innocuousness of Benzalkonium Chloride on the Eye Concerning Possible Growth of Langerhans Cells
University of Rostock2 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2006年12月22日最近更新:
适应症
相关药物
试验速览
- 阶段
- 1 期
- 发起方
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- Possible raised Langerhans cell density in the corneal epithelium
研究概览
简要总结
The study analysis the influence of benzalkonium chloride on the density of antigen presenting Langerhans cells. This is achieved in a double blind randomized study using in-vivo confocal microscopy to identify and quantify Langerhans cells of the human cornea in its central and peripheral part. This study design is based on observations with raised Langerhans cell density after the application of benzalkonium chloride containing eye drops in glaucoma patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •healthy probands
排除标准
- •eye diseases
- •pregnancy and lactation period
- •drug dependency
结局指标
主要结局
Possible raised Langerhans cell density in the corneal epithelium
次要结局
未报告次要终点
研究者
研究点 (2)
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