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Clinical Trials/NCT00183586
NCT00183586
Completed
Phase 2

Treatment for Adolescent Anorexia Nervosa

University of Chicago1 site in 1 country121 target enrollmentApril 2004

Overview

Phase
Phase 2
Intervention
Not specified
Conditions
Eating Disorders
Sponsor
University of Chicago
Enrollment
121
Locations
1
Primary Endpoint
Weight (BMI)
Status
Completed
Last Updated
9 years ago

Overview

Brief Summary

This study will compare specific family therapy, standard family systems therapy, and standard individual psychotherapy to determine which is most effective in treating adolescent anorexia nervosa.

Detailed Description

In adolescents, anorexia nervosa severely affects physical, emotional, and social development. Despite the seriousness and prevalence of adolescent anorexia nervosa, few studies have focused on the effectiveness of various types of psychotherapy treatment. Family-based therapy may be an effective approach to treating adolescent anorexia nervosa. This study will compare specific family therapy (FT), standard family systems therapy (FS), and standard individual psychotherapy (IT) to determine which is most effective in treating adolescent anorexia nervosa. The study also aims to determine potential predictors and moderators of outcomes, as well as the cost-benefit ratio of each treatment. Participants in this open-label study will be randomly assigned to one of three treatment groups. Group 1 will receive FT, Group 2 will receive FS, and Group 3 will receive IT. All participants will receive a total of 24 hours of their assigned therapy over a period of 12 months. Study visits will occur at baseline, immediately post-intervention, and again six months and one year post-intervention. Weight change will be assessed, as well as changes in concerns about weight and shape. The cost-benefit ratio of the treatments will also be evaluated.

Registry
clinicaltrials.gov
Start Date
April 2004
End Date
March 2009
Last Updated
9 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Meets Diagnostic and Statistical Manual (4th Edition) (DSM-IV) criteria for anorexia nervosa

Exclusion Criteria

  • Any psychotic illness

Outcomes

Primary Outcomes

Weight (BMI)

Time Frame: Measured at end-of-treatment and Months 6 and 12 post-treatment

Secondary Outcomes

  • Changes in shape and weight concerns as measured with Eating Disorder Examination subscales(Measured at end-of-treatment and Months 6 and 12 post-treatment)

Study Sites (1)

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