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临床试验/NCT00183586
NCT00183586已完成2 期

Treatment for Adolescent Anorexia Nervosa

University of Chicago1 个研究点 分布在 1 个国家目标入组 121 人开始时间: 2004年4月1日最近更新:
适应症
干预措施

试验速览

阶段
2 期
状态
已完成
入组人数
121
试验地点
1
主要终点
Weight (BMI)

研究概览

简要总结

This study will compare specific family therapy, standard family systems therapy, and standard individual psychotherapy to determine which is most effective in treating adolescent anorexia nervosa.

详细描述

In adolescents, anorexia nervosa severely affects physical, emotional, and social development. Despite the seriousness and prevalence of adolescent anorexia nervosa, few studies have focused on the effectiveness of various types of psychotherapy treatment. Family-based therapy may be an effective approach to treating adolescent anorexia nervosa. This study will compare specific family therapy (FT), standard family systems therapy (FS), and standard individual psychotherapy (IT) to determine which is most effective in treating adolescent anorexia nervosa. The study also aims to determine potential predictors and moderators of outcomes, as well as the cost-benefit ratio of each treatment.

Participants in this open-label study will be randomly assigned to one of three treatment groups. Group 1 will receive FT, Group 2 will receive FS, and Group 3 will receive IT. All participants will receive a total of 24 hours of their assigned therapy over a period of 12 months. Study visits will occur at baseline, immediately post-intervention, and again six months and one year post-intervention. Weight change will be assessed, as well as changes in concerns about weight and shape. The cost-benefit ratio of the treatments will also be evaluated.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Single Group
主要目的
Diagnostic
盲法
None

入排标准

年龄范围
12 Years 至 18 Years(Child, Adult)
性别
All
接受健康志愿者
否

入选标准

  • •Meets Diagnostic and Statistical Manual (4th Edition) (DSM-IV) criteria for anorexia nervosa

排除标准

  • •Any psychotic illness

研究组 & 干预措施

1

Experimental

Participants will receive family-based treatment

干预措施: Family therapy (FT) (Behavioral)

2

Active Comparator

Participants will receive individual adolescent focused therapy

干预措施: Individual therapy (IT) (Behavioral)

结局指标

主要结局

Weight (BMI)

时间窗: Measured at end-of-treatment and Months 6 and 12 post-treatment

次要结局

  • Changes in shape and weight concerns as measured with Eating Disorder Examination subscales(Measured at end-of-treatment and Months 6 and 12 post-treatment)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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