Effects of Eccentric Training in the Rehabilitation of Patients Undergoing Anterior Cruciate Ligament Reconstruction: a Randomized Controlled Trial

Not Applicable

Recruiting

• Conditions: Anterior Cruciate Ligament Reconstruction Rehabilitation; Anterior Cruciate Ligament Reconstruction

• Registration Number: NCT06905691
• Lead Sponsor: Federal University of Health Science of Porto Alegre

Brief Summary

This study aims to investigate the effects of eccentric training on the functional rehabilitation of patients undergoing Anterior Cruciate Ligament Reconstruction (ACL-R). Thirty-four participants undergoing ACL-R will be randomly assigned to two groups: the Conventional Training Group (CTG) and the Eccentric Training Group (ETG). Both groups will adhere to the same post-surgical rehabilitation program, commencing in the first week after ACL-R and continuing until the criteria for sports resumption are achieved. The rehabilitation program will be structured into four phases: immediate post-operative, preparatory, general acquisition, and specific acquisition. The key distinction between the groups lies in their exercise regimen: ETG will prioritize the eccentric phase of movement, whereas CTG will engage in conventional exercises, maintaining uniform load across both movement phases. Assessment procedures will be conducted at three intervals for all participants: immediately post-operative, at 12 weeks post-ACL-R surgery (before the initiation of the training protocol), and at 25 weeks post-ACL-R surgery (upon completion of the training protocol). The primary outcome measure will be the maximum isometric strength of knee extensors. Secondary outcomes will encompass functional status, maximum isometric strength of knee flexors, peak dynamic strength during leg press, quadriceps muscle atrophy, performance in jump tests, and psychological readiness.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2024-04-03
• Study Start: 2025-03-01
• Study First Submitted QC: 2025-03-31
• Status Verified: 2025-04
• Study First Posted: 2025-04-01
• Last Update Submitted: 2025-04-22
• Last Update Posted: 2025-04-24
• Primary Completion: 2026-09
• Study Completion: 2026-12

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 34

Inclusion Criteria

• Individuals of both genders, aged between 18 and 40 years, scheduled for ACL reconstruction surgery during the data collection period.

Exclusion Criteria

• Delay of more than 7 days after surgery to initiate the rehabilitation program proposed by the study;
• Presence of injuries related to the rupture of the ACL that hinder partial weight-bearing in the first week after surgery, either due to medical recommendation or the patient inability/disposition.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Maximal isometric strength of knee extensors	In the 12th and 25th weeks post-surgery	Assessed by manual isometric dynamometry

Secondary Outcome Measures

Name	Time	Method
Maximum dynamic strength during leg press exercise	In the 12th and 25th weeks post-surgery	Assessed through the 1 maximum repetition test (1RM)
Performance in jump tests	In the 12th and 25th weeks post-surgery	Measured through the Single and Triple Hop Tests
Psychological readiness to return to sport	In the 12th and 25th weeks post-surgery.	Assessed by Return to Sport after Anterior Cruciate Ligament Reconstruction Surgery (RSI-ACL)
Maximum isometric strength of knee flexors	In the 12th and 25th weeks post-surgery	Assessed by manual isometric dynamometry
Muscle atrophy	In the 12th and 25th weeks post-surgery	The evaluation of muscle atrophy will be performed by measuring the circumference of the thigh (cm)
Self-reported functional impairments	In the 12th and 25th weeks post-surgery.	Self-reported functional impairments will be assessed using the International Knee Documentation Committee (IKDC)

Trial Locations

Locations (1)

Private Rehabilitation Center; 🇧🇷 Veranópolis, RS, Brazil