Assessment of Niacinamide Cosmetic Product Efficacy in Model of Irritant Contact Dermatitis

Not Applicable

Recruiting

• Conditions: Contact Dermatitis

• Registration Number: NCT06331390
• Lead Sponsor: University of Split, School of Medicine

Brief Summary

Testing the effectiveness and safety of cosmetics with niacinamide in irritant contact dermatitis: A Randomised, Controlled Trial will be conducted at USSM. Healthy volunteers will be included (at least 25) and test sites are forearms. Sodium lauryl sulphate will be used to induce contact dermatitis and participants will be measured for 7 days

Detailed Description

The efficacy of niacinamide cosmetic product on contact dermatitis will be evaluated using Courage Khazaka device and probes for hydration, redness and transepidermal water loss

Study Timeline

• Status Verified: 2024-03
• Study First Submitted: 2024-03-19
• Study First Submitted QC: 2024-03-19
• Last Update Submitted: 2024-03-19
• Study First Posted: 2024-03-26
• Last Update Posted: 2024-03-26
• Study Start: 2024-04
• Primary Completion: 2024-06
• Study Completion: 2024-07

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

• young, healthy volunteers who gave written informed consent

Exclusion Criteria

• skin disease, skin damage on measurement sites, use of corticosteroids and immunomodulators a month prior to the inclusion and during the trial, non-adherence to the trial protocol, exposure to artificial UV radiation, pregnancy and lactation

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
tewameter	day 1- day 7	measurement of transepidermal water loss on skin, objective and non invasive

Trial Locations

Locations (1)

University of Split School of Medicine; 🇭🇷 Split, Croatia