Assessment of Niacinamide Cosmetic Product Efficacy in Model of Irritant Contact Dermatitis
Not Applicable
Recruiting
- Conditions
- Contact Dermatitis
- Interventions
- Other: placeboOther: niacinamide cosmetic product
- Registration Number
- NCT06331390
- Lead Sponsor
- University of Split, School of Medicine
- Brief Summary
Testing the effectiveness and safety of cosmetics with niacinamide in irritant contact dermatitis: A Randomised, Controlled Trial will be conducted at USSM. Healthy volunteers will be included (at least 25) and test sites are forearms. Sodium lauryl sulphate will be used to induce contact dermatitis and participants will be measured for 7 days
- Detailed Description
The efficacy of niacinamide cosmetic product on contact dermatitis will be evaluated using Courage Khazaka device and probes for hydration, redness and transepidermal water loss
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 25
Inclusion Criteria
- young, healthy volunteers who gave written informed consent
Exclusion Criteria
- skin disease, skin damage on measurement sites, use of corticosteroids and immunomodulators a month prior to the inclusion and during the trial, non-adherence to the trial protocol, exposure to artificial UV radiation, pregnancy and lactation
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description placebo placebo nothing intervenition niacinamide cosmetic product immortela cosmetic product
- Primary Outcome Measures
Name Time Method tewameter day 1- day 7 measurement of transepidermal water loss on skin, objective and non invasive
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University of Split School of Medicine
ðŸ‡ðŸ‡·Split, Croatia