Oral drug therapy as palliative chemotherapy in Head and Neck cancers
- Conditions
- Health Condition 1: null- Metasatatic ,recurrent or locally advanced head and neck cancers deemed unsuitable for loco-regional treatment.Histologically proven squamous cell cancer
- Registration Number
- CTRI/2014/07/004791
- Lead Sponsor
- Tata Memorial Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 110
Metasatatic ,recurrent or locally advanced head and neck cancers deemed unsuitable for loco-regional treatment.
Histologically proven squamous cell cancer
Age group 18-70years
Karnofsky performance status more than or equal to 70
Normal pretreatment haemaotological and biochemical parameters as defined below
Haemoglobin:8-18mg/dl
Absolute Neutrophil count more than 1000/mm3
Total leucocyte count 3000-10,000/mm3
Platelet count -1-4lakhs/mm3
S urea and S creatnine below 45 and 1.2 respectively.
Serum Creatinine clearance more than 60
Fasting blood sugar less than 120
Baseline Liver function test within twice the normal limits
Primary in thyroid,salivary gland or nasopharynx
patients with significant and uncontrolled comorbid conditions like DM,Hypertension,COPD,active tuberculosis and HIV positive patients
Patients who have received cisplatin within last 3 months
serological positive for HIV,HCV and HBV
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method