Cardio-Pulmonary Exercise Testing in Healthy Population

Not Applicable

• Conditions: Healthy Obesity, Metabolically
• Interventions: Other: exercise test

• Registration Number: NCT05242211
• Lead Sponsor: The Baruch Padeh Medical Center, Poriya

Brief Summary

Introduction: Cardiopulmonary exercise test (CPET) is a helpful tool for evaluation of aerobic exercise capacity and tolerance for variety of population. The test progression include an incremental stepwise or ramp control protocol to exhaustion There are different methods used in various clinical setting. CPET involves the measurement of respiratory gas exchange i.e. oxygen uptake, carbon dioxide, minute ventilation, other variables while monitoring ECG, blood pressure, pulse oximetry and exertion perceived (Borg Scale) during an incremental test on a cycle-ergo meter or treadmill. This test allow to assess an integrative exercise responses to submaximal and maximal effort.

Aim: To compere exercise responses and achieved criteria for maximal exercise testing with different exercise protocol Methods: Healthy volunteers (normal and overweight ) will be recruited to participants in the study. Demographics (age, sex), anthropometric (height, weight, abdominal circumference), will be measured. By using questionnaire, physical activity behavior and motivation toward engage in physical activity will be filled by the participants. Each participants will conducted an exercise test on treadmill (using Modified Bruce Protocol) and cycle ergometer. Quark CPET metabolic cart (Cosmed, Rome, Italy) will be used to collect and analysis gas exchange. 10 minute after the graded exercise test Supra maximal exercise test (SMT) will be done for 2 minutes one stage (treadmill protocol) or 10% at cycle protocol higher than highest load achieved in the incremental test.

All exercise parameter done on the different ergometer will be compared

Detailed Description

Not available

Study Timeline

• Study Start: 2019-11-03
• Study First Submitted: 2021-12-19
• Status Verified: 2022-02
• Study First Submitted QC: 2022-02-06
• Last Update Submitted: 2022-02-06
• Study First Posted: 2022-02-16
• Last Update Posted: 2022-02-16
• Primary Completion: 2022-09-30
• Study Completion: 2022-09-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

• Healthy 18-55

Exclusion Criteria

• Physical activity limitation due to orthopedic , neurological and cognition deficit Pregnancy children

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Healthy	exercise test	Healthy participants will do both cycle ergometer and treadmill exercise

Primary Outcome Measures

Name	Time	Method
RPE-rate of perceived exertion	through study completion, an average of 1 year	rate of perceived exertion on a 10 point modified Borg scale
Max heart rate	through study completion, an average of 1 year	Max heart rate
VO2 MAX	through study completion, an average of 1 year	maximal oxygen consumption

Trial Locations

Locations (1)

The BARUCH PADEH Medical Center, Poriya; 🇮🇱 Teverya, The Lower Galilee, Israel