taVNS on Pupillary Response and Perceptual Learning
Not Applicable
Recruiting
- Conditions
- Pupillary Response
- Interventions
- Procedure: Transcutaneous Auricular Vagal Nerve Stimulation (taVNS)Procedure: Sham Stimulation
- Registration Number
- NCT05386563
- Lead Sponsor
- NYU Langone Health
- Brief Summary
This study has two parts. The study team will evaluate transcutaneous auricular vagal nerve stimulation (taVNS) and two sham settings during a passive task while measuring pupillary response. Second, the study team will assign either taVNS, sham, or no intervention during a go/no-go task and evaluate perceptual learning over three sessions which will also include measuring the pupillary response and electroencephalogram (EEG).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
- Healthy individuals 18 to 65
- Normal audiometric testing
Exclusion Criteria
- Co-morbidities including cardiomyopathies, arrhythmias
- Implantable devices including vagal stimulators, pacemakers
- Presence of metallic implants
- Pregnancy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Transcutaneous Auricular Vagal Nerve Stimulation (taVNS) Transcutaneous Auricular Vagal Nerve Stimulation (taVNS) - Sham Sham Stimulation -
- Primary Outcome Measures
Name Time Method Change in Time It Takes to Reach 90% of Asymptotic Level Performance Baseline, Month 3 Will be measured during performance on a go/no-go task.
Change in Speed of Learning to Perform a Behavioral Task Baseline, Month 3 Will be measured during performance on a go/no-go task.
Change in Overall Mean Peak (Pupillary Response) Baseline, Month 3 Pupillary responses will be measured noninvasively using a video camera during a go/no-go task.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
NYU Langone Health - Bellevue Hospital
🇺🇸New York, New York, United States