Bisphosphonate-coated Dental Implants

University Hospital, Linkoeping1 site in 1 country16 target enrollmentOctober 2008

ConditionsEdentatio (Toothlessness)

Overview

Phase: Phase 2
Intervention: Not specified
Conditions: Edentatio (Toothlessness)
Sponsor: University Hospital, Linkoeping
Enrollment: 16
Locations: 1
Primary Endpoint: Increase in resonance vibration frequency (ISQ units) from insertion to abutment connection as compared to the control in the same patient.
Status: Completed
Last Updated: 12 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Dental implants (screws for fastening false teeth) have been coated with bisphosphonates (drugs that slow down removal of bone). Patients get one such screw and one without coating, by a surgeon who does not know which is which. The screws are compared by measuring how well fixed they are by a vibration measuring technique, and x-rays. The hypothesis is that the bisphosphonates will improve fixation.

Registry

clinicaltrials.gov

Start Date

October 2008

End Date

June 2011

Last Updated

12 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

University Hospital, Linkoeping

Responsible Party

Principal Investigator

Per Aspenberg

professor

University Hospital, Linkoeping

Eligibility Criteria

Inclusion Criteria

•Need for at least 2 dental implants, which are to be inserted in bone of reasonably similar quality.

Exclusion Criteria

•Systemic or immunologic disease, alcoholism, uncontrolled diabetes and smoking.
•Local exclusion criteria were: previous tumour, trauma and surgery.
•Also patients with Cawood \& Howell class IV - VI maxilla-bone were excluded.