“Effect of Addition of Buprenorphine or Dexamethasone or Dexmedetomidine to Levobupivacaine on Postoperative Analgesia in Ultrasound guided transversus abdominis plane block in patients undergoing unilateral Inguinal Hernia Repair: a Prospective Randomized Double Blind Controlled Trial

Effect of addition of buprenorphine or dexamethasoneor dexmedetomidine to levobupivacaine on postoperative analgesia in ultrasoundguided transversus abdominis plane block in patients undergoing unilateralinguinal hernia repair: a prospective randomized double blind controlled trial is the study.90 patients aged between 18to 70 years with the American Society of Anesthesiologists classification (ASA)class 1 and 2 candidates for elective surgery under regional anesthesia at SriLakshmi Narayana Institute Of Medical Sciences with Inclusioncriteria :Patients willing to participate in the  study,ASA I &II,Patient age 18-70 years of either sex and Elective  surgery under general anesthesia withendotracheal intubation cases

Exclusioncriteria : has ASA 3 or more,Patients with history of risk factorsfor perioperative aspiration of gastric contents,history of chronic obstructive pulmonarydisease, asthma,history of recent respiratoryinfections,duration of surgery more than 3 h wereexcluded from the study, Pregnant and lactating mother and with study variables include General parameters i.e. Age, Gender, weight, heightand  Duration of surgery and duration ofanesthesia.the time taken to request for the first analgesic,totalrescue analgesic doses in the first 24 h, and the NRS score(0 = no pain, 10 =intolerable pain) just after the TAP block and at intervals of e  at intervals of 0,2,4,6,8,10,12,15,18,21and 24hrs postoperatively.Statistical analysis were performed using theIBM Statistical Package for the Social Sciences (SPSS) for windows, version22.0 (SPSS Inc., USA). Numerical data were analyzed by using an unpairedStudents t-test. Categorical data were analyzed by the chi square test orFisher’s exact test as appropriate. The differences among the 3 groups wereanalyzed by using the one-way analysis of variance (ANOVA) test.