NCT05600634招募中不适用
Multi Center Clinical Observation of Sentinel Skin Graft From the Same Donor Source for Detecting Acute Rejection After Renal Transplantation
Second Affiliated Hospital, School of Medicine, Zhejiang University3 个研究点 分布在 1 个国家目标入组 24 人开始时间: 2024年1月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 24
- 试验地点
- 3
- 主要终点
- 2017 Banff Kidney Transplantation Rejection Rating
研究概览
简要总结
The purpose of this study was to explore the accuracy of sentinel skin grafts from the same donor source in diagnosing renal allograft rejection, and to provide new ideas and options for the later clinical diagnosis of renal allograft rejection. Further, try to provide timing guidance for early immunization intervention.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with end-stage renal disease undergoing renal transplantation;
- •18-60 years old;
- •Postoperative follow-up points are complete (visit the hospital every week in the first month after surgery, every two weeks in 2-3 months, every four to six months, and every three months in 7-12 months. Follow up at any time when skin rejection is observed. The follow-up time may be adjusted when the condition changes);
- •The participants had good compliance, volunteered to participate in the test and signed the informed consent form.
排除标准
- •Untreated or disseminated malignant tumor;
- •Active period of infectious diseases;
- •Serious cardiovascular disease occurred recently;
- •Combined with other important organ failure;
- •History of mental illness or cognitive impairment;
结局指标
主要结局
2017 Banff Kidney Transplantation Rejection Rating
时间窗: Through study completion, an average of 1 year
A rating evaluation on kidney rejection
2007-edition Banff skin containing allogeneic composite histopathological diagnosis grading
时间窗: Through study completion, an average of 1 year
Skin histopathological diagnosis
Renal function testing
时间窗: Through study completion, an average of 1 year
Blood Cr and Bun testing
次要结局
- Renal ultrasound diagnosis(Through study completion, an average of 1 year)
- Complications(Through study completion, an average of 1 year)
研究者
研究点 (3)
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