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Pathophysiology of diaphragm fatigue in patients with systolic heart failure

Recruiting
Conditions
I50.1
Left ventricular failure
Registration Number
DRKS00016544
Lead Sponsor
Institut für Schlafmedizin und neuromuskuläre Erkrankungen, Universitätsklinikum Münster
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
20
Inclusion Criteria

a. Age > 18 years (no age limit)
b. able to consent
c. Diagnosis of systolic heart failure in accordance with the latest available ESC/HF (European Society of Cardiology - Heart Failure) guideline (Ponikowski et al. 2016) (HFrEF)

Exclusion Criteria

- Severe psychiatric disease including dementia
-Thoracic wall disease
-Cardiac pacemaker

Study & Design

Study Type
observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Twitch trans-diaphragmatic pressure after magnetic cervical stimulation of the phrenic nerves [cmH2O] (on the day of the appointment in our laboratory and before, during and after diaphragm fatigue has been reached)
Secondary Outcome Measures
NameTimeMethod
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