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Clinical Trials/NCT03024203
NCT03024203
Completed
Not Applicable

A Comparison of Cognitive Training Approaches in Psychotic Disorders

Queen's University1 site in 1 country70 target enrollmentAugust 2016

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Psychotic Disorders
Sponsor
Queen's University
Enrollment
70
Locations
1
Primary Endpoint
Change in Functional Performance - Specific Levels of Functioning (SLOF) from Baseline
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

Cognitive remediation (CR) is the best treatment to improve neurocognitive abilities for individuals with psychosis, however, there is no gold standard method of cognitive remediation available. Cognitive training refers to the training component of CR in which people practice computerized exercises that train specific cognitive abilities. There is no agreed upon approach within the field as to the type of training that is most effective with some studies, training higher level cognitive abilities, some training perceptual abilities, and others training general cognitive skills. This study will directly compare two competing methods of cognitive training on measures of neurophysiology, neurocognition, functional competence, and real-world functional performance.

Registry
clinicaltrials.gov
Start Date
August 2016
End Date
March 2018
Last Updated
7 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Dr. Christopher Bowie

Principal Investigator

Queen's University

Eligibility Criteria

Inclusion Criteria

  • psychotic disorder
  • No previous cognitive remediation in past 6 months

Exclusion Criteria

  • Brain injury
  • Substance abuse
  • Neurocognitive disorder
  • Developmental Disability

Outcomes

Primary Outcomes

Change in Functional Performance - Specific Levels of Functioning (SLOF) from Baseline

Time Frame: Post-treatment (within 2 weeks following the end of treatment)

Rating scale completed by participants' case managers that rates their ability to perform different everyday tasks

Secondary Outcomes

  • Change in Neurocognition - MATRICS Cognitive Consensus Battery (MCCB) from Baseline(Follow-Up (3 months after the end of treatment))
  • Change in Neurophysiology - EEG from Baseline(Follow-Up (3 months after the end of treatment))
  • Functional Competence - Canadian Objective Assessment of Life Skills Brief (COALS-B) from Baseline(Follow-Up (3 months after the end of treatment))
  • Change in Functional Performance - Specific Levels of Functioning (SLOF) from Baseline(Follow-Up (3 months after the end of treatment))

Study Sites (1)

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