Prevalence Study of the Etiology of Pregnancy Anemia

• Conditions: Pregnancy Anemia

• Registration Number: NCT03448432
• Lead Sponsor: University Hospital, Brest

Brief Summary

Anemia during pregnancy occurs in 41% of women. The most common etiology is iron deficiency, but studies to determine prevalence of other causes of anemia in pregnancy are still lacking. However, anemia in pregnancy lead to adverse pregnancy outcomes and increase risk of maternal and fœtal morbidity and mortality. Specific management of anemia is so needed.

Detailed Description

Not available

Study Timeline

• Status Verified: 2018-02
• Study First Submitted: 2018-02-22
• Study First Submitted QC: 2018-02-22
• Study Start: 2018-02-27
• Study First Posted: 2018-02-28
• Last Update Submitted: 2018-03-02
• Last Update Posted: 2018-03-05
• Primary Completion: 2019-10-27
• Study Completion: 2019-12-27

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 700

Inclusion Criteria

• woman 18-years or older
• woman with a normal pregnancy
• anemia with accidental or symptomatic discovery, whatever the term of pregnancy
• non opposition collected

Exclusion Criteria

• Refuse to participate
• Stopped pregnancy whatever the term
• Medical abortion of pregnancy

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Prevalence of the etiologies of anemias occured during pregnancy	from date of inclusion until 6 weeks after delivery	Anemia in pregnancy is defined as hemoglobin level (Hb) \< 11 g/dL in the first and the third trimesters, and Hb \< 10.5 g/dL in the second trimester.

Secondary Outcome Measures

Name	Time	Method
Study of obstetrical complications in women with anemia	from date of inclusion until delivery	* Measure of the incidence of postpartum haemorrhage, instrumental extractions, caesareans sections, premature delivery, intra-uterine growth restriction or small for gestational age, placenta abruption, preeclampsia and low birth-weight newborn (\<3rd and \<10th percentile under neonatal morphometry curves); * Level of release,; * 1-, 3- and 5-minutes Apgar score,; * Arterial ans venous cord potential hydrogen (pH)
Study of the evolution of anemia during pregnancy and postpartum	from date of inclusion until 6 weeks after delivery	Measure of the Hb level monthly and at 6 weeks after delivery
Describe the etiological and therapeutic management of pregnancy anemias	from date of inclusion until 6 weeks after delivery	therapeutic management : etiologic treatment (supplemental iron, vitaminic replacement, others) and symptomatic treatment (numbers and rhythm of transfusions)

Trial Locations

Locations (1)

CHRU de Brest; 🇫🇷 Brest, France