Dutch multidomain lifestyle intervention in older adults at risk of cognitive decline - FINGER

Vrije Universiteit Medisch Centrum0 个研究点目标入组 1,206 人开始时间: 待定最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•- 60-79 years of age at pre-screening;
•- Adequate fluency in Dutch to understand the informed consent and complete
•(online) questionnaires ;
•- Providing informed consent to all study procedures;
•- Internet access at home
•- >=3 (self-reported) risk factors (must contain at least 2 modifiable risk
•factors and 1 non-modifiable risk factor):
•Modifiable risk factors:
•- Physical inactivity (1)
•- Unhealthy diet (1)
•- Low mental/cognitive activity (1)
•- High blood pressure (1)
•- High cholesterol (1)
•- High body mass index (BMI) (2)
•Non-modifiable risk factors:
•- First-degree family history of dementia
•- Subjective cognitive decline/memory complaints
•(1) Measured using LIBRA questionnaire;
•(2) Defined as >=25 kg/m2 for 60-69 years old, and >=28 kg/m2 for >=70 years old,
•based on self-reported height and weight.

•1. Diagnosis of dementia or mild cognitive impairment at baseline
•(self-reported);
•2. Significant cognitive impairment assessed using a validated
•telephone-administered cognitive battery (TICSm score<23).
•3. Conditions affecting safe and continuous engagement in the intervention
•(e.g. under treatment for current malignant diseases, major psychiatric
•disorders (e.g. major depression, psychosis, bipolar disorder), neurological
•disorders (e.g. Parkinson*s disease, multiple sclerosis), symptomatic
•cardiovascular disease (e.g. stroke, angina pectoris, heart failure, myocardial
•infarction), re-vascularization within three months, severe loss of vision,
•hearing or communicative ability, severe mobility impairment, other conditions
•preventing co-operation) as judged by the local study nurse or consulted
•physician at the local study site;
•4. Coincident participation in any other intervention trial at time of
•pre-screening.
•5. Coincident participation of spouse/partner in the FINGER-NL trial.

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