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Dry Needling vs Injection in Patients With Temporomandibular Disorders

Not Applicable
Recruiting
Conditions
Temporomandibular Disorders
Interventions
Procedure: Injection and placebo dry needling
Procedure: Placebo dry needling and placebo injection
Procedure: Dry needling and placebo injection
Procedure: Dry needling and injection
Registration Number
NCT04726683
Lead Sponsor
Josue Fernandez Carnero
Brief Summary

The main objective is to compare the effectiveness of dry needling in improving pain and disability versus placebo, and versus infiltration, in patients with myofascial temporomandibular dysfunction in the short, medium and long term.

Detailed Description

Not available

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
64
Inclusion Criteria
  1. Subjects aged between 18 and 60 years.
  2. Pain of more than 6 weeks of evolution in the craniofacial region.
  3. TMD with origin in the masticatory musculature according to the "DC-TMD" criteria.
Exclusion Criteria
  1. Previous injection or dry needling intervention (3 months) on the masseter muscle.
  2. Arthrogenous TMD.
  3. History of trauma, infection in the temporomandibular joint in the last 6 months.
  4. Coagulation disorders.
  5. Pregnancy.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
InjectionInjection and placebo dry needlingTrigger point injection of lidocaine on an active myofascial trigger point of the masseter muscle.
PlaceboPlacebo dry needling and placebo injectionCombines sham dry needling + sham injection.
Dry needlingDry needling and placebo injectionTrigger point dry needling on an active myofascial trigger point of the masseter muscle.
Dry needling + InjectionDry needling and injectionCombines experimental dry needling and injection
Primary Outcome Measures
NameTimeMethod
Pain perception (Change is being assessed)At baseline, 24h post treatment, at one month, at six months and at twelve months

Self reported Visual Analog Scale. Minimum value is 0 (best); Maximun value is 10 (worst).

Secondary Outcome Measures
NameTimeMethod
Beck Depression Inventory (BDI)At baseline, 24h post treatment, at one month, at six months and at twelve months

The level of depressive symptomatology was measured by the Spanish version of the Beck Depression Inventory (BDI-II); a 21-item self-report rating scale that assesses affective, cognitive and somatic symptoms of depression. Each answer being scored on a scale value of 0 to 3. Higher total scores indicate more severe depressive symptoms.

Believability of placeboAt one week, at two weeks, at three weeks, at for weeks

Patients beliefs about group allocation: A scale of cale of four options (Experimental Dry needling / Experimental Injection / Placebo Comparator / Active Comparator) in which patients had to indicate which intervention they believe they have received during the treatment sessions.

Pain body mapAt baseline, 24h post treatment, at one month, at six months and at twelve months

The patient will be asked to paint the areas where he/she presents pain. This map consists of a representation of a person drawn in an anterior, posterior and two lateral planes. The drawing is in a grid of 10mm x 10mm, 16mm x 16 mm cells, up to a maximum of 256 cells.

Conditioned pain modulationAt baseline, 24h post treatment, at one month, at six months and at twelve months

Pressure pain thresholds measure on the distal phalanx of the thumb before and during the application of a noxious stimulus ( Ischemic pain)

Central sensitization inventoryAt baseline, 24h post treatment, at one month, at six months and at twelve months

It serves to identify the symptoms related to central sensitization. It consists of 25 items that are scored from 0: never to 4: always reaching a maximum score of 100. Results are interpreted as follows: subclinical = 0 to 29; mild = 30 to 39; moderate = 40 to 49; severe = 50 to 59; and extreme = 60 to 100.

Mandibular DynamicAt baseline, 24h post treatment, at one month, at six months and at twelve months

Interincisal distance measured in cm.

DisabilityAt baseline, 24h post treatment, at one month, at six months and at twelve months

Self-reported disability questionnaire: Craniofacial Pain and Disability Inventory (CF-PDI).

The CF-PDI contains 21 items divided into 2 subscales according to their content and exploratory factor analysis: "pain and disability" and "jaw functional status."

Temporal summation (TS)At baseline, 24h post treatment, at one month, at six months and at twelve months

Initially, a needlle stimulus is measured locally and distally. Then, the TS is triggered by 10 consecutive pressures on the PPT at the pressure determined at each location. For each pulse, the pressure was gradually increased at a rate of 2 kg/s at the determined PPT and held for 1 s before being released (with an interval of one second between each stimulus).

Fair avoidance beliefs (FAB questionnaire)At baseline, 24h post treatment, at one month, at six months and at twelve months

Fear-avoidance Beliefs Questionnaire . The instrument consists of two subscales, a four-item physical activity subscale, and a seven-item work subscale. Each item is scored from 0 to 6 and summed to produce the subscale score. Possible scores range from 0-28 to 0-42, with higher scores indicating greater fear avoidance beliefs.

Pressure pain threshold (Change is being assessed)At baseline, 24h post treatment, at one month, at six months and at twelve months

Digital algometer measure of the pressure pain threshold on the masseter muscle

Anxiety (STAI questionnaire)At baseline, 24h post treatment, at one month, at six months and at twelve months

The state-trait anxiety inventory (STAI) is a questionnaire that measures trait anxiety (a personality factor that predisposes the patient to suffer from anxiety) and the state of anxiety (environmental factors that protect or generate anxiety). Each of the two sub-scales (trait anxiety and state anxiety) consists of 20 items, ranging from 0 (nothing) to 3 (a lot).

Expectation of improvementBaseline, at one week, at two weeks, at three weeks, at for weeks

Patients´ expectations of pain improvement after the intervention. Patients report their estimated pain perception after the treatment by completing a Self reported Visual Analog Scale. Minimum value is 0 (best); Maximun value is 10 (worst).

Kinesiophobia (TAMPA scale)At baseline, 24h post treatment, at one month, at six months and at twelve months

Tampa Scale for Kinesiophobia. To assess the fear of movement and pain-related fear. The 11 items are scored 1-4, with total scores ranging from 11 to 44. The addition of all the points obtained from each of the items results in the level of kinesiophobia, with higher scores indicating greater perceived kinesiophobia

EQ-5DAt baseline, 24h post treatment, at one month, at six months and at twelve months

. It consists of two parts: the descriptive EQ-5D system and the VAS. It is a generic and standardized questionnaire, self-administered, simple to answer and with low cognitive load.

Pain catastrophizing (PCS)At baseline, 24h post treatment, at one month, at six months and at twelve months

Pain catastrophizing Scale (PCS). This tool is a 13-item questionnaire designed to measure the three components of pain-related catastrophizing: rumination, magnification, and helplessness, resulting in a unique score. Each item is responded to on a 5-point scale (0 not at all, 4 all the time) relating the degree to which the individual experiences a thought or feeling of a painful situation.

Neuropathic painAt baseline, 24h post treatment, at one month, at six months and at twelve months

The presence of neuropathic pain will be assessed using the DN4 questionnaire validated in Spanish. This clinician-administered questionnaire consists of 10 questions. Seven of them are related to the quality of pain and are based on the patient interview, and the remaining three are based on clinical examination according to the presence or absence of hypoesthesia and tactile allodynia to pressure and touch.

Trial Locations

Locations (1)

Clínica Universitaria de la Universidad Rey Juan Carlos

🇪🇸

Alcorcón, Madrid, Spain

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