Three-dimensional photographic imaging of children with orofacial clefts; A longitudinal cohort study into 3D facial growth of children with non-syndromic orofacial clefts (OFC)
- Conditions
- schisiscleft palate
- Registration Number
- NL-OMON30900
- Lead Sponsor
- niversitair Medisch Centrum Sint Radboud
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 105
Inclusion Criteria
The patient inclusion criteria are non-syndromic UCLP or BCLP. Infants should be born at term (38+ wk) and both parents should be Caucasisch for both the case and control group.
Exclusion Criteria
Other congenital malformations and soft tissue bands. In addition no oral clefts have occured in the first, second or third degree relatives of the control child.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Differences in soft tissue facial growth between case and control group will be<br /><br>evaluated by measurement of three-dimensional facial volume changes and changes<br /><br>in landmark position over time during the first 6 years of life.</p><br>
- Secondary Outcome Measures
Name Time Method <p>Not applicable</p><br>